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Kinetics of extracellular ATP in mastoparan 7-activated human erythrocytes
(Elsevier, 2013-10)
Background: The peptide mastoparan 7 (MST7) stimulated ATP release in human erythrocytes. We explored intraand extracellular processes governing the time-dependent accumulation of extracellular ATP (i.e., ATPe kinetics). ...
Extracellular ATP regulates FoxO family of transcription factors and cell cycle progression through PI3K/Akt in MCF-77 cells
(Elsevier, 2013-09)
Background: Forkhead Box-O (FoxO) transcription factors regulate the expression of many genes involved in suppression. Released nucleotides can regulate intracellular signaling pathways through membrane-bound purinergic ...
Extracellular ATP and nitric oxide impact on cell viability in tomato suspension cells
(Nova Science Publishers, 2010)
Adenosine triphosphate has been largely studied as an energetic intracellular molecule in plants. However there is growing evidences that extracellular metabolism of ATP has a great impact on plant cell physiology. In this ...
Extracellular ATP, nitric oxide and superoxide act coordinately to regulate hypocotyl growth in etiolated Arabidopsis seedlings
(Elsevier Gmbh, 2009-12)
Etiolated Arabidopsis thaliana seedlings germinated in the presence of reducing buffers such as reduced gluthathione (GSH) and dithiothreitol (DTT) have altered morphology. GSH and DTT inhibited hypocotyl elongation in a ...
Blocking ATP-releasing channels prevents high extracellular ATP levels and airway hyperreactivity in an asthmatic mouse model
(AMER PHYSIOLOGICAL SOC, 2021)
Allergic asthma is a chronic airway inflammatory response to different triggers like inhaled allergens. Excessive ATP in fluids from patients with asthma is considered an inflammatory signal and an important autocrine/paracrine ...
Extracellular ATP hydrolysis in Caco-2 human intestinal cell line
(Elsevier Science, 2021-10)
Extracellular nucleotides and nucleosides activate signaling pathways that play major roles in the physiology and pathophysiology of the gastrointestinal tract. Ectonucleotidases hydrolyze extracellular nucleotides and ...
Dynamic regulation of extracellular ATP in Escherichia coli
(Portland Press, 2017-04)
We studied the kinetics of extracellular ATP (ATPe) in Escherichia coli and their outer membrane vesicles (OMVs) stimulated with amphipatic peptides melittin (MEL) and mas-toparan 7 (MST7). Real-time luminometry was used ...