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Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer
(Elsevier Ireland, 2001-03)
Epidemiological evidence links alcohol intake with increased risk in breast cancer. Not all the characteristics of the correlation can be explained in terms of changes in hormonal factors. In this work, we explore the ...
Rat breast microsomal biotransformation of ethanol to acetaldehyde but not to free radicals: Its potential role in the association between alcohol drinking and breast tumor promotion
(Wiley, 2003-12)
We recently showed that mammary cytosolic xanthineoxidoreductase had the ability to bioactivate ethanol (EtOH) to acetaldehyde (AC) and free radicals. In thepresent study, we report that the microsomal fraction also ...
Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid
(Taylor & Francis, 2004-01)
There is a well-established association between alcohol consumption and breast cancer risk. About 4% of the breast cancers in developed countries are estimated to be attributable to drinking alcohol. The mechanism of tumor ...
Alcohol drinking and mammary cancer: Pathogenesis and potential dietary preventive alternatives
(Baishideng, 2014-10)
Alcohol consumption is associated with an increased risk of breast cancer, increasing linearly even with a moderate consumption and irrespectively of the type of alcoholic beverage. It shows no dependency from other risk ...
Relación de los cánceres de próstata y de mama con el consumo de alcoholProstate and Breast Cancer: Their Relationship with Alcohol Intake
(Sociedad Iberoamericana de Información Científica, 2010-09)
Además del hábito de fumar y de la alimentación, el consumo de alcohol es uno de los factores de riesgo más importantes para los cánceres humanos. Las localizaciones del organismo asociadas con este riesgo incluyen el ...
Effects of propolis and phenolic acids on triple-negative breast cancer cell lines: Potential involvement of epigenetic mechanisms
(2020-03-02)
Triple-negative breast cancer is an aggressive disease frequently associated with resistance to chemotherapy. Evidence supports that small molecules showing DNA methyltransferase inhibitory activity (DNMTi) are important ...