Buscar
Mostrando ítems 1-10 de 180
A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes
(Nature Publishing Group, 2019-04)
The rate of RNA polymerase II (RNAPII) elongation has an important role in the control of alternative splicing (AS); however, the in vivo consequences of an altered elongation rate are unknown. Here, we generated mouse ...
Maintenance of murine embryonic stem cells' self-renewal and pluripotency with increase in proliferation rate by a bovine granulosa cell line-conditioned medium
(Mary Ann Liebert, 2011-08)
Murine embryonic stem cells (mESCs) are pluripotent cells that can be propagated in an undifferentiated state in continuous culture on a feeder layer or without feeders in the presence of leukemia inhibitory factor (LIF). ...
Polysome profiling followed by RNA-seq of cardiac differentiation stages in hESCs
(Nature Research, 2018)
Diferenciación y caracterización espectroscópica de células madre embrionarias de ratón a células pancreáticas
(2018-09-13)
RESUMEN: Una necesidad fundamental en la medicina contemporánea, es encontrar una fuente renovable de células para reemplazar células enfermas y tejidos dañados. El valor de las células madre embrionarias (ESC) para la ...
Knockdown of E2F2 Inhibits Tumorigenicity, but Preserves Stemness of Human Embryonic Stem Cells
(New Rochelle, 2014)
Tumorigenicity of human pluripotent stem cells is a major threat limiting their application in cell therapy protocols. It remains unclear, however, whether suppression of tumorigenic potential can be achieved without ...
Expressão de ativina A em células-tronco embrionárias de camundongo durante o processo de diferenciação em osteoblastos
(Universidade Federal de Minas GeraisUFMG, 2013-03-01)
The search for anabolic agents has been widely researched for osteoporosis therapy. Embryonic stem cells (ESC), differentiated into osteoblasts, have been used for the study of cell physiology. Protocols osteoblastic cell ...
Phosphoproteomics Profiling Suggests a Role for Nuclear beta IPKC in Transcription Processes of Undifferentiated Murine Embryonic Stem Cells
(AMER CHEMICAL SOC, 2010)
Protein kinase C (PKC) plays a key role in embryonic stem cell (ESC) proliferation, self-renewal and differentiation However, the function of specific PKC Isoenzymes have yet to be determined Of the PKCs expressed in ...
Obtención de células renales a partir de células madre embrionarias de ratón y su aplicación en un modelo murino con lesión renal
(2018-10-01)
RESUMEN: Las enfermedades renales son un problema de salud mundial. En la actualidad, más
de 2 millones de personas requieren terapias sustitutivas como diálisis o trasplante,
sin embargo, dichos tratamientos están ...
Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture
(Public Library of Science, 2020)