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ErbB-2 nuclear function in breast cancer growth, metastasis and resistance to therapy
(BioScientifica, 2016-10)
Approximately 15-20% of breast cancers (BC) show either membrane overexpression of ErbB-2 (MErbB-2), a member of the ErbBs family of receptor tyrosine kinases, or ERBB2 gene amplification. Until the development of ...
Genetic variants related to angiogenesis and apoptosis in patients with glioma
(Academia Brasileira de Neurologia - ABNEURO, 2018-06)
The role of the Neuregulin-1/Erbb signaling pathway in cardiac morphogenesis and remodeling
(Sociedad Argentina de Fisiología, 2014-02)
Neuregulin-1 (NRG1) signaling through tyrosine kinase receptors erbB2 and erbB4 was revealed essential for cardiac development as mouse mutated in the Nrg1 or either cognate receptors Erbb2 or Erbb4 genes lack the formation ...
Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
(Baishideng Publishing Group, 2014-07)
Neuregulin-1 (NRG1) signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis, and it plays an essential role in maintaining the myocardial architecture during adulthood. The ...
Imuno-expressao das proteinas catepsina B, heparanase, c-ERBB-2 em carcinoma espinocelular de orofaringe
(Universidade Federal de São Paulo (UNIFESP), 2007)
Transcriptome changes induced by docetaxel in human mammary cell lines expressing different levels of ERBB2
(SPANDIDOS PUBL LTD, 2009)
The taxane docetaxel is currently the most effective chemotherapeutic drug for the treatment of advanced breast cancer. However, a considerable proportion of breast cancer patients do not respond positively to docetaxel. ...
Efectos nucleares del receptor Tirosina Quinasa ErbB-2 en cáncer de mama
(Ediciones Médicas del Sur, 2017-08)
Aproximadamente 15-20% de los cánceres de mama (CM) presentan sobre- expresiónen la membrana citoplasmáticade ErbB-2 (MErbB-2), un miembro de la familia ErbBs de receptores con actividad de tirosina quinasa, o bien presentan ...