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Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal
(Elsevier, 2015-03)
The nicotine (NIC) withdrawal syndrome is considered to be a major cause of the high relapse rate among individuals undergoing smoking cessation. The aim of the present study was to evaluate a possible role of GABAB receptors ...
Studies for the transformation of carbocycles into carbohydrates: approach toward the synthesis of higher sugar derivatives
(Elsevier Sci LtdOxfordInglaterra, 2004)
alpha 4 beta 2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2006-08)
Alpha 4 and beta 2 nicotinic acetylcholine receptor ( nAChR) subunits expressed heterologously assemble into receptors with high (HS) and low (LS) sensitivity to acetylcholine (ACh); their relative proportions depend on ...
In vivo effects of 3-iodocytisine: Pharmacological and genetic analysis of hypothermia and evaluation of chronic treatment on nicotinic binding sites
(Elsevier Ltd., 2009-05-19)
Several cytisine derivatives have been developed in the search for more selective drugs at nicotinic
acetylcholine receptors (nAChR). Binding experiments in transfected cell lines showed that the iodination
of cytisine ...
From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research
(ELSEVIER SCI LTD, 2005-12)
S-Nicotine, the principal psychoactive constituent of Nicotiana tabacum, underpins addiction to tobacco smoking. Although tobacco consumption is a leading cause of death worldwide, nicotine itself is also proposed to have ...
α4β2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
(2006)
α4 and β2 nicotinic acetylcholine receptor (nAChR) subunits expressed heterologously assemble into receptors with high (HS) and low (LS) sensitivity to acetylcholine (ACh); their relative proportions depend on the α4 to ...