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Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes
(Public Library of Science, 2019-08)
Enzymes of the M32 family are Zn-dependent metallocarboxypeptidases (MCPs) widely distributed among prokaryotic organisms and just a few eukaryotes including Trypanosoma brucei and Trypanosoma cruzi, the causative agents ...
Distribution of angiotensin-(1-7) and ACE2 in human placentas of normal and pathological pregnancies
(W B SAUNDERS CO LTD, 2006)
This work was designed to study the expression of the vasodilator peptide angiotensin-(1-7) [Ang-(1-7)] and its generating enzyme (ACE2) in the uteroplacental interface. Placentas were obtained from 11 early pregnancy ...
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension
(1999-05-06)
In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather ...
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension
(1999-05-06)
In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather ...
Efeito do lisinopril sobre parametros cardiacos e mortalidade no infarto experimental em ratos
(1997-03-01)
Purpose: To analyse the effect of early (<24 h) administration of lisinopril on ventricular remodeling and mortality after myocardial infarction (MI) in rats. Methods: Wistar rats weighing 200-250 g were submitted to ...
Efeito do lisinopril sobre parametros cardiacos e mortalidade no infarto experimental em ratos
(1997-03-01)
Purpose: To analyse the effect of early (<24 h) administration of lisinopril on ventricular remodeling and mortality after myocardial infarction (MI) in rats. Methods: Wistar rats weighing 200-250 g were submitted to ...