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Enzyme mimic of heterobimetallic Cu(II) and Fe(III) tetrapyridylporphine modified nanoparticles
(Elsevier Science, 2011-12)
The covalent binding of the porphyrin to immobilized gold nanoparticles resulted in a very useful and simple method to evaluate the absorption spectroscopy of a monolayer of porphyrins and the spectral changes produced by ...
Bioinspired functional mimics of the manganese catalases
(Elsevier Science Sa, 2012-06)
Catalase enzymes are present in most aerobic forms of life and are responsible for the decomposition of hydrogen peroxide to molecular oxygen and water. Although most catalases contain the iron-protoporphyrin IX prosthetic ...
Tuning the MnII 2/MnIII 2 redox cycle of a phenoxo-bridged diMn catalase mimic with terminal carboxylate donors
(Elsevier Science Inc, 2018-05)
A new phenoxo-bridged diMnIII complex, Na[Mn2L(OH)2(H2O)2]·5H2O (1), obtained with the ligand L5− = 5‑methyl‑2‑hydroxo‑1,3‑xylene‑α,α‑diamine‑N,N,N′,N′‑tetraacetato, has been prepared and characterized. Mass spectrometry, ...
Molecular dynamics simulation of halogen bonding mimics experimental data for cathepsin L inhibition
(2015)
A MD simulation protocol was developed to
model halogen bonding in protein–ligand complexes by
inclusion of a charged extra point to represent the anisotropic
distribution of charge on the halogen atom. This
protocol ...
Síntese e caracterização de complexos de Cu(II) bioinspirados no sítio ativo de oxigenases
(Universidade Tecnológica Federal do ParanáCuritibaBrasilBacharelado em QuímicaUTFPR, 2021-12-02)
Inorganic chemistry is the science that studies the behavior, properties and structures of inorganic compounds, showing numerous applications and ramifications. Bioinorganic aims, in general, to study the role and behavior ...
Erythrocyte ghost cell-alkaline phosphatase: construction and characterization of a vesicular system for use in biomineralization studies
(Elsevier B.V., 2002-12-23)
Alkaline phosphatase is required for the mineralization of bone and cartilage. This enzyme is localized in the matrix vesicle, which plays a role key in calcifying cartilage. In this paper we standardize a method to ...
Erythrocyte ghost cell-alkaline phosphatase: construction and characterization of a vesicular system for use in biomineralization studies
(Elsevier B.V., 2002-12-23)
Alkaline phosphatase is required for the mineralization of bone and cartilage. This enzyme is localized in the matrix vesicle, which plays a role key in calcifying cartilage. In this paper we standardize a method to ...
Construction of an alkaline phosphatase-liposome system: a tool for biomineralization study
(Elsevier B.V., 2002-09-01)
Alkaline phosphatase is required for the mineralization of bone and cartilage. This enzyme is localized in the matrix vesicle, which plays a role key in calcifying cartilage. In this paper. we standardize a method for ...
Allosteric inhibition of a-thrombin enzymatic activity with ultrasmall gold nanoparticles
(Royal Society of Chemistry, 2018-09-24)
The catalytic activity of enzymes can be regulated by interactions with synthetic nanoparticles (NPs) in
a number of ways. To date, however, the potential use of NPs as allosteric effectors has not been
investigated in ...