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Avaliação imunoistoquímica do EGFR / Her -1 em leucoplasias bucais
(Universidade Federal de Minas GeraisUFMG, 2009-07-08)
Leukoplakia is the most common precancerous lesion of the oral cavity.The presence of epithelial dysplasia and clinical characteristics such as tobacco consumption and location are important predicting factors of malignant ...
EGFR amplification and expression in oral squamous cell carcinoma in young adults
(2018-07-01)
The aim of this study was to investigate epidermal growth factor receptor (EGFR) gene alterations in two groups of patients with oral squamous cell carcinoma (OSCC) (a test group of subjects aged ≤40 years and a control ...
Dysregulation and detection methods of EGFR in oral cancer. A narrative review
(Facultad de Ciencias, 2016)
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein, with an intracellular domain and tyrosine kinase function (TK) involved in cell proliferation. Dysfunctions in EGFR signaling pathways have been ...
Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
(FRONTIERS RESEARCH FOUNDATION, 2013)
Sonic hedgehog modulates egfr dependent proliferation of neural stem cells during late mouse embryogenesis through egfr transactivation
(FRONTIERS RESEARCH FOUNDATION, 2013)
EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinases
(Elsevier Inc., 2004)
Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are ubiquitous receptors involved in
the control of a variety of cellular processes frequently found altered in cancer cells. ...
Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
(2013-09)
Sonic Hedgehog (Shh/GLI) and EGFR signaling pathways modulate Neural Stem Cell (NSC) proliferation. How these signals cooperate is therefore critical for understanding normal brain development and function. Here we report ...
Balsas lipídicas são necessárias para a translocação do receptor lipídicas são necessárias para a translocação do receptor do fator de crescimento epidermal para o núcleo
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2010-08-19)
The epidermal growth factor receptor (EGFR) regulates cellular process
of ligands such as EGF and transforming growth factor alpha (TGF-α). Upon
activation EGFR initiates signaling cascades that can result in cell ...