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CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
(Elsevier, 2001)
CYP1A1, CYP2E1 and GSTM1 polymorphisms were evaluated in Chilean healthy controls and lung cancer patients. In the
Chilean healthy group, frequencies of CYP1A1 variant alleles for MspI (m2 or CYP1A1*2A) and ile/val (val ...
E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells
(Taylor & Francis, 2015-04)
E2F transcription factors regulate a wide range of biological processes, including the cellular response to DNA damage. In the present study, we examined whether E2F family members are transcriptionally induced following ...
Síntese de triazolopirimidinas 7-triclorometil e triazolopirimidinonas substituídas a partir de reações entre 4-alcóxi-1,1,1-tricloro-3-alquen-2-onas e 3-amino-1H-1,2,4-triazóis
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2013-08-02)
A synthetic strategy was developed for obtaining a series of new 7-
trichloromethyl-[1,2,4]-triazolo-[1,5-a]pyrimidines substituted from cyclocondensation
reaction between 4-alkoxy-1,1,1-trichloro-3-alken-2-ones (enones ...
Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
(Elsevier, 1999)
Many investigators have reported an association between genetic polymorphisms of cytochromes P-450 CYP2E1, CYP1A1
or glutathione S-transferase Mu (GSTM1) and susceptibility to lung cancer. However, pronounced interethnic ...