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Effect of dimerization on the mechanism of action of aurein 1.2
(2016-06-01)
The mechanism of action of antimicrobial peptides depends on physicochemical properties such as structure, concentration, and oligomerization. Here, we focused on the effect of dimerization on the mechanism of action of ...
The dynamic action mechanism of small cationic antimicrobial peptides
(Royal Society Of Chemistry, 2014-09)
Antimicrobial peptides form part of the immune system as protection against the action of external pathogens. The differences that exist between mammalian and microbial cell membrane architectures<br />are key aspects of ...
Small molecule stabilization of non-native protein-protein interactions of SARS-CoV-2 N protein as a mechanism of action against COVID-19
(Taylor & Francis, 2020-12-28)
The outbreak of COVID-19, the disease caused by SARS-CoV-2, continues to affect millions of people around the world. The absence of a globally distributed effective treatment makes the exploration of new mechanisms of ...
Lagrangian reduction of nonholonomic discrete mechanical systems
(American Institute of Mathematical Sciences, 2010-03)
In this paper we propose a process of lagrangian reduction and<br />reconstruction for nonholonomic discrete mechanical systems where the action of a continuous symmetry group makes the configuration space a principal ...
Princípio de ação quântica de Schwinger
(2013-12-01)
The Schwinger quantum action principle is a dynamic characterization of the transformation functions and is based on the algebraic structure derived from the kinematic analysis of the measurement processes at the quantum ...
Combining Experimental Evidence and Molecular Dynamic Simulations To Understand the Mechanism of Action of the Antimicrobial Octapeptide Jelleine-I
(Amer Chemical Soc, 2014-07-29)
Jelleines are four naturally occurring peptides that comprise approximately eight or nine C-terminal residues in the sequence of the major royal jelly protein 1 precursor (Apis mellifera). The difference between these ...
PLA2-like proteins myotoxic mechanism: A dynamic model description
(2017-12-01)
Phospholipase A2-like (PLA2-like) proteins contribute to the development of muscle necrosis in Viperidae snake bites and are not efficiently neutralized by current antivenom treatments. The toxic mechanisms of PLA2-like ...
Self-organization and action: A systemic approach to common action
(2018-01-01)
This chapter investigates the assumptions and implications of the mechanistic approach to action. First, some of the central theses of classical mechanics are investigated, and it is noted that given the dualist ontology ...