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Evaluation of ceftiofur-PHBV microparticles in rats
(Dove Medical Press Ltd., 2014)
Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface
(ELSEVIER SCIENCE INC, 2013-07-01)
A transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were ...
A rabbit model demonstrates the influence of cartilage thickness on intra-articular drug delivery and retention within cartilage
(Orthopaedic Research Society. Published by Wiley Periodicals, Inc., 2015)
For evaluation of new approaches to drug delivery into cartilage, the choice of an animal model is critically important. Since cartilage thickness varies with animal size, different levels of drug uptake, transport and ...
A rabbit model demonstrates the influence of cartilage thickness on intra-articular drug delivery and retention within cartilage
(Orthopaedic Research Society. Published by Wiley Periodicals, Inc., 2015)
For evaluation of new approaches to drug delivery into cartilage, the choice of an animal model is critically important. Since cartilage thickness varies with animal size, different levels of drug uptake, transport and ...
Multiscale boundary conditions for non-Fickian diffusion applied to drug-eluting stents
(2017-01-01)
We propose a multiscale model for the study of blood flow, plasma filtration, and non-Fickian mass transport by a coronary drug-eluting stent. We derive an analytic solution of a one-dimensional model for non-Fickian ...
Synthesis, cytotoxicity and in vitro antileishmanial activity of naphthothiazoles
(2013-06-01)
The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...
Molecular modeling databases: A new way in the search of protein targets for drug development
(2007-01-01)
DBMODELING is a relational database of annotated comparative protein structure models and their metabolic, pathway characterization. It is focused on enzymes identified in the genomes of Mycobacterium tuberculosis and ...