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Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour
(Macmillan Publishers LtdLondon, 2014-06-09)
Wilms tumour (WT) is an embryonal kidney neoplasia for which very few driver genes have been identified. Here we identify DROSHA mutations in 12% of WT samples (26/222) using whole-exome sequencing and targeted sequencing ...
Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4
(FUNPECInmunovirologíaRibeirão Preto, Brasil, 2023)
Efeito do choque térmico durante a maturação in vitro na expressão de micrornas em oócitos e embriões bovinos
(Universidade Federal de Juiz de Fora (UFJF)BrasilICB – Instituto de Ciências BiológicasPrograma de Pós-graduação em Ciências Biológicas: Imunologia e Doenças Infecto-Parasitárias/Genética e BiotecnologiaUFJF, 2019)
FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus
(Humana Press, 2019-07)
Rett syndrome is a complex neurodevelopmental disorder that is mainly caused by mutations in MECP2. However, mutations in FOXG1 cause a less frequent form of atypical Rett syndrome, called FOXG1 syndrome. FOXG1 is a key ...
Identification of a Specific miRNA Profile in HIV-Exposed Seronegative Individuals
(Lippincott Williams & Wilkins, 2016-09-01)
Objective:MicroRNAs (miRNAs) are small noncoding RNAs involved in the posttranscriptional regulation of gene expression that play important roles in viral infections. Alterations of specific miRNAs are described in HIV ...
Análise exploratória sobre os mirtrons: uma visão da bioinformática
(Universidade Tecnológica Federal do ParanáCornelio ProcopioBrasilEngenharia de ComputaçãoUTFPR, 2016-06-30)
In recent years, several research has elucidated alternative ways of miRNA biogenesis, that instead of using the Drosha process are derived by cleavage of the splicing process. It corresponds to a mechanism that gave rise ...
Toward the human cellular microRNAome
(2017)
MicroRNAs are short RNAs that serve as regulators of gene expression and are essential components of normal development as well as modulators of disease. MicroRNAs generally act cell-autonomously, and thus their localization ...
Chronic low-dose exposure to a mixture of environmental endocrine disruptors induces microRNAs/isomiRs deregulation in mouse concomitant with intratesticular estradiol reduction
(2017)
Humans are environmentally exposed not only to single endocrine-disrupting chemicals (EDCs) but to mixtures that affect their reproductive health. In reproductive tissues, microRNAs (miRNAs) are emerging as key targets of ...
Identificação, caracterização de miRNAs e sua via de processamento em Lanistes nyassanus e Marisa cornuarietismiRNAs identification, characterization and their processing pathway in Lanistes nyassanus and Marisa cornuarietis
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Biotecnologia, 2022)