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Reversed-phase high-performance liquid chromatography: A fast and efficient analytical method to quantify docetaxel-loaded pegylated liposomes in release study
(2021-01-01)
Docetaxel is an anticancer that belongs to the family of taxanes and acts in the inhibition of cell proliferation through the polymerization of microtubules. The aim of this study was the development and validation of a ...
Transcriptome changes induced by docetaxel in human mammary cell lines expressing different levels of ERBB2
(SPANDIDOS PUBL LTD, 2009)
The taxane docetaxel is currently the most effective chemotherapeutic drug for the treatment of advanced breast cancer. However, a considerable proportion of breast cancer patients do not respond positively to docetaxel. ...
A Critical Review of Properties and Analytical Methods for the Determination of Docetaxel in Biological and Pharmaceutical Matrices
(2018-11-02)
Docetaxel (DTX) is an antineoplastic agent of the second generation of the taxoid family. It is a semi-synthetic drug prepared from a precursor extracted of the plant Taxus baccata. The commercial formulation of DTX, ...
Transferrin-functionalized liposomes for docetaxel delivery to prostate cancer cells
(2021-02-20)
Prostate cancer (PC) is the second type of cancer, causing the greatest number of deaths among the male population in the world. An attractive approach to treat PC involves the superficial modification of liposomes with ...
Eficacia y seguridad del uso de Docetaxel en cáncer de próstata metastásico resistente a la castración
(Universidad Peruana Cayetano HerediaPE, 2023)
Un resultado de laboratorio de PSA alto es el indicador más sensible de que un paciente tiene cáncer de próstata, hiperplasia o próstata benigna, el crecimiento es lento pero con alcance clínico significativo, el propósito ...
EGFR-targeted immunoliposomes efficiently deliver docetaxel to prostate cancer cells
(2020-10-01)
Prostate cancer is the second cause of cancer death in men worldwide. Docetaxel (DTX), an antimitotic drug, is widely used for the treatment of metastatic prostate cancer patients. Taxotere® is a commercial DTX formulation. ...
Efeito do docetaxel e da dexametasona nas propriedades mecânicas e na histologia dos pulmões
(2015-12-01)
Introducão: A prevalência estimada de pneumonia induzida por docetaxel e de 10% sendo fatal em 40% dos casos e os corticóides são rotineiramente utilizados para reduzir a incidência de náuseas, vômitos e de síndrome de ...
Rational design of polymer-lipid nanoparticles for docetaxel delivery
(Elsevier Science, 2019-03)
In this work, a stable nanocarrier for the anti-cancer drug docetaxel was rational designed. The nanocarrier was developed based on the solid lipid nanoparticle preparation process aiming to minimize the total amount of ...