Buscar
Mostrando ítems 1-10 de 120
Geração de encefalinas pela endooligopeptidase e de cérebro bovino: substratos e inibidores da enzima
(Universidade Federal de São Paulo (UNIFESP), 1987)
SGLT-2 inhibitors for people with type 2 diabetes.
(Elsevier, 2019)
Evidence that sodium-glucose co-transporter-2 inhibitors (SGLT2i) can reduce cardiovascular risk—with trials showing reductions in cardiovascular death, myocardial infarction, and stroke—would suggest they have much to ...
Você conhece esta síndrome?
(Soc Brasileira Dermatologia, 2008-07-01)
Papillon-Lefevre syndrome, or palmoplantar keratoderma with periodontitis, is a rare genodermatosis with cutaneous and dental repercussions. the condition appears at around the first year of life, with transgressive ...
Anti-tumor necrosis factor-α therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis
(2005)
Objective. To assess the enzymatic activity and biochemical status of dipeptidyl peptidase IV (DPP IV), an enzyme that participates in the degradation of proinflammatory molecules, in sera from a group of patients with ...
Effects of Dipeptidyl-Peptidase 4 Inhibitor about Vascular Inflammation in a Metabolic Syndrome Model
(Public Library of Science, 2014-09)
Background: In this study, we used vidagliptin(V) to examine the role of the DDP-IV, incretin system component, in the activation of different molecular inflammatory cytokines, NF-kB and VCAM-1 to generate a microenvironment ...
Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4
(American Society of Biochemistry Molecular Biology, 2020)
Sitagliptin's effects on bone tissue and osseointegration in diabetic rats
(2019-06-01)
Objective: To investigate the effects of sitagliptin, a dipeptidyl peptidase 4 inhibitor used to treat type II diabetes, on bone tissue and on implant osseointegration in diabetic rats. Design: Thirty-two male rats were ...