Now showing items 1-10 of 17
A comparative study on the 1,3-dipolar cycloadditions of diazomethane and bis(diisopropylamino)phosphinodiazomethane to chiral electron-deficient olefins: Reactivity and diastereoselectivity
(Pergamon-Elsevier Science Ltd, 2002-11)
The 1,3-dipolar cycloadditions of bis(diisopropylamino)phosphinodiazomethane, 10, to chiral electron-deficient olefins have been investigated for the first time. The results have been compared with those corresponding to ...
FURTHER CHARACTERIZATION of BOTHROPAIN, A CYSTEINE PEPTIDASE FROM the PLASMA of the SNAKE BOTHROPS-JARARACA
(Elsevier B.V., 1993-03-01)
1. A new procedure was developed for the isolation of bothropain from Bothrops jararaca plasma. the previously used proteolytic digestion step was abolished and HPLC was introduced for the final purification.2. Comparison ...
Synthesis of indazol-4,7-dione derivatives as potential trypanocidal agents
The synthesis of new indazol-4,7-dione derivatives via 1,3-dipolar cycloaddition of diazomethane with 2,3-dimethyl-1,4-benzoquinone (2) and 1,4-naphthoquinone (7) followed by N-alkylation of the pyrazol nitrogen atom of ...
INHIBITORS of the MAJOR CYSTEINYL PROTEINASE (GP57/51) IMPAIR HOST-CELL INVASION and ARREST the INTRACELLULAR DEVELOPMENT of TRYPANOSOMA-CRUZI INVITRO
(Elsevier B.V., 1992-06-01)
Peptidyl diazomethane (PDAM) derivatives, a class of irreversible inhibitors for cysteine proteinase, were screened for the ability to impair Trypanosoma cruzi invasion and intracellular development in primary cultures of ...
Estudio fitoquímico de Pistacia mexicana
(Universidad Michoacana de San Nicolás de Hidalgo, 2020-02)
Hexane extracts were obtained from the fruits and stems of Pistacia mexicana, from which β-sitosterol (1) and masticadienonic acid (2) were isolated, obtaining the latter in significant quantities. Using 2 as starting ...
A New ent-Clerodane Diterpene from Hymenaea courbaril var. altissima
(Sociedade Brasileira de Química, 2002)
Synthesis of methyl dihydrohardwickiate and its C-4 epimer. Structural amendment of natural crolechinic acid
(Pergamon-elsevier Science LtdOxfordInglaterra, 2000)
Clerodane-type diterpenes from the seed pods of Hymenaea courbaril var. stilbocarpa
(Pergamon-elsevier Science LtdOxfordInglaterra, 2001)