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Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives
(Hindawi Publishing Corporation, 2016)
The prevalence of cardiac diabetic diseases has been increased around the world, being the most common cause of death and disability among diabetic patients. In particular, diabetic cardiomyopathy is characterized with a ...
Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives
(Hindawi Publishing Corporation, 2016)
The prevalence of cardiac diabetic diseases has been increased around the world, being the most common cause of death and disability among diabetic patients. In particular, diabetic cardiomyopathy is characterized with a ...
Diabetic cardiomyopathy and metabolic remodeling of the heart
(2013)
The incidence and prevalence of diabetes mellitus are both increasing rapidly in societies around the globe.
The majority of patients with diabetes succumb ultimately to heart disease, much of which stems from
atherosclerotic ...
Intravenous administration of bone marrow-derived multipotent mesenchymal stromal cells has a neutral effect on obesity-induced diabetic cardiomyopathy
(Sociedad de Biología de Chile, 2013)
Obesity is a major global health issue. Obese patients develop metabolic syndrome, which is a cluster of clinical features characterized by insulin resistance and dyslipidemia. Its cardiac manifestation, diabetic cardiomyopathy, ...
Intravenous administration of bone marrow-derived multipotent mesenchymal stromal cells has a neutral effect on obesity-induced diabetic cardiomyopathy
(Sociedad de Biología de Chile, 2013)
Obesity is a major global health issue. Obese patients develop metabolic syndrome, which is a cluster of clinical features characterized by insulin resistance and dyslipidemia. Its cardiac manifestation, diabetic cardiomyopathy, ...
Novel insights into the pathogenesis of diabetic cardiomyopathy and pharmacological strategies
(Frontiers Media, 2021)
Diabetic cardiomyopathy (DCM) is a severe complication of diabetes developed mainly in
poorly controlled patients. In DCM, several clinical manifestations as well as cellular and
molecular mechanisms contribute to its ...
New Molecular Insights of Insulin in Diabetic Cardiomyopathy
(2016)
Type 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide. Cardiovascular disorders generated as a consequence of T2DM are a major cause of death related to this disease. Diabetic cardiomyopathy (DCM) is ...
Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene
(Federation Amer Soc Exp Biol, 2004-05-01)
Diabetic cardiomyopathy includes fibrosis. Kallikrein (KLK) can inhibit collagen synthesis and promote collagen breakdown. We investigated cardiac fibrosis and left ventricular (LV) function in transgenic rats (TGR) ...
Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy
(Elsevier, 2015)
Diabetic cardiomyopathy (DCM) is a common consequence of longstanding type 2 diabetes mellitus (T2DM) and
encompasses structural, morphological, functional, and metabolic abnormalities in the heart.Myocardial energy
metabolism ...
Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy
(PLoS, 2013)
BACKGROUND/AIM:
Hypercaloric diet ingestion and sedentary lifestyle result in obesity. Metabolic syndrome is a cluster of clinical features secondary to obesity, considered as a pre-diabetic condition and recognized as ...