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Cellular and molecular mechanisms of apoptosis in skeletal muscle atrophy
(2007-12-28)
Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal and integumentary systems. The role of apoptosis in post-mitotic tissues, such as skeletal ...
CaMKII-dependent ryanodine receptor phosphorylation mediates sepsis-induced cardiomyocyte apoptosis
(Wiley Blackwell Publishing, Inc, 2020-09)
Sepsis is associated with cardiac dysfunction, which is at least in part due to cardiomyocyte apoptosis. However, the underlying mechanisms are far from being understood. Using the colon ascendens stent peritonitis mouse ...
Apoptosis of Lactotrophs Induced by D2 Receptor Activation Is Estrogen Dependent
(Karger, 2008-02)
BACKGROUND/AIMS: Dopamine (DA) inhibits prolactin release and reduces lactotroph proliferation by activating D2 receptors. DA and its metabolite, 6-hydroxydopamine (6-OHDA), induce apoptosis in different cell types. DA ...
AGEING INDUCES APOPTOSIS AND INCREASES HSP70 STRESS PROTEIN IN THE EPIDIDYMIS OF Octodon degus
(Sociedad Chilena de Anatomía, 2004)
Brazilian green propolis induced apoptosis in human lung cancer A549 cells through mitochondrial-mediated pathway
(2015)
Propolis effect on the growth and apoptosis of human lung adenocarcinoma (A549 cells) was investigated as well as its mechanisms. Cells were incubated with propolis for 72 h, and 3-(4,5- dimethylthiazol-2-yl)-2,5-dipheny ...
Hyperosmotic stress promotes endoplasmic reticulum stress‑dependent apoptosis in adult rat cardiac myocytes
(Springer, 2019-07-15)
In diferent pathological situations, cardiac cells undergo hyperosmotic stress and cell shrinkage. This change in cellular volume has been associated with contractile dysfunction and cell death. However, the intracellular ...
Antibody-targeted horseradish peroxidase associated with indole-3-acetic acid induces apoptosis in vitro in hematological malignancies
(Pergamon-Elsevier B.V. Ltd, 2011-05-01)
Indole-3-acetic acid (IAA), when oxidized by horseradish peroxidase (HRP), is transformed into cytotoxic molecules capable of inducing cell injury. The aim of this study was to test if, by targeting hematopoietic tumors ...