Purpose Granule cells pathology in dentate gyrus, have received considerable attention in terms of understanding the pathophysiology of temporal lobe epilepsy with hippocampal sclerosis. The aim of this study was to determine ...

Neuroplasticity has been investigated considering the neuronal growth-associated phosphoprotein as a marker of neuronal adaptive capabilities. in the present work, studying the hippocampal reorganization observed in the ...

Endocannabinoid receptors CB1R and CB2R are present in the CNS and modulate synaptic activity. By using an in vitro model, two concentrations of CB1R agonist ACEA at 0.5 and 5 μM doses and CB1R antagonist AM251 at 1 and ...

Previous studies have shown that strength exercise improves memory and increases expression of a myriad of proteins involved on neuronal survival and synaptic plasticity in the hippocampus. Conversely, chronic exposure to ...

The hippocampus is implicated in the generation of memory and learning, processes which involve extensive neuroplasticity. The generation of hippocampal adult-born neurons is particularly regulated by glial cells of the ...

Traumatic Brain Injury (TBI) is one of the major health problems worldwide. Emerging evidence has been pointed out TBI as a public health concern, especially by affecting individuals at working age (under 45 years old) and ...

Neuroplasticidade refere-se à capacidade que o sistema nervoso possui em modificar algumas das suas propriedades morfológicas e funcionais em resposta às alterações do ambiente, em apoio à aprendizagem e em resposta às ...

La población mundial envejece en forma acelerada. Considerando que el deterioro cognitivo es uno de los principales determinantes de enfermedad y discapacidad de los adultos mayores, la comprensión de sus mecanismos f ...