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A Critical Review of Properties of Darunavir and Analytical Methods for Its Determination
(Taylor & Francis Inc, 2014-01-02)
Darunavir is a synthetic non-peptidic protease inhibitor that has been shown to be extremely potent against wild-type HIV, and it is an important component of highly active antiretroviral treatment (HAART), which is ...
Characteristics, complexation and analytical methods of darunavir
(2014)
What is it? Darunavir is a protease inhibitor used in the treatment of HIV infection. It is an important drug of therapy cocktail for patients infected with the virus. On the market there are darunavir ethanolate tablets ...
Influence of Darunavir: β-cyclodextrin complex on the solubility of Darunavir
(2014)
Darunavir, a protease inhibitor used in the treatment of HIV infection, was complexed with β-cyclodextrin because of its low solubility in water and poor bioavailability, with the objective of improving the solubility of ...
Development and validation of infrared spectroscopy method for the determination of darunavir in tabets
(Scientific and Academic Publishing, 2013)
Darunavir is a protease inhibitor used in the treatment of HIV infection. It is a pillar of therapy cocktail for patients with this virus. This work proposed the development and validation of an infrared spectroscopy method ...
Development and validation of infrared spectroscopy method for the determination of darunavir in tabets
(Scientific and Academic Publishing, 2016)
Development and validation of first derivative spectrophotometric method for quantification of darunavir in tablets
(2014)
Aims: Darunavir is widely used in HIV/AIDS therapy. It is a HIV protease inhibitor that has excellent efficacy against the virus. The aim of this study is to develop and validate an analytical method fast and free of ...
Análise quimico-farmacêutica de Darunavir etanolato em comprimidos e de seu complexo de inclusão
(Universidade Estadual Paulista (Unesp), 2015-04-07)
The work aimed the formation of complex darunavir:β-cyclodextrin and the study of the consequences of complexation, as well as development and validation of analytical methods for qualitative and quantitative determination ...
Darunavir: A Critical Review of Its Properties, Use and Drug Interactions
(Karger, 2012-01-01)
Darunavir is a synthetic nonpeptidic protease inhibitor which has been shown to be extremely potent against wildtype HIV as well as a large panel of PI-resistant clinical isolates and shows a high genetic barrier to the ...
Darunavir: A Critical Review of Its Properties, Use and Drug Interactions
(Karger, 2012-01-01)
Darunavir is a synthetic nonpeptidic protease inhibitor which has been shown to be extremely potent against wildtype HIV as well as a large panel of PI-resistant clinical isolates and shows a high genetic barrier to the ...