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MAPK pathways regulation by DUSP1 in the development of osteosarcoma: Potential markers and therapeutic targets
(Wiley, 2017)
Osteosarcoma (OS) is the most frequent primary bone tumor that affect children and adolescents. This tumor is highly aggressive with high risk of metastasis and the implementation of new drugs has not been successful. The ...
p38-Map kinase negatively regulates the slow force response to stretch in rat myocardium through the up-regulation of dual specificity phosphatase 6 (DUSP6)
(Cell Physiol Biochem Press, 2019-02-28)
Background/Aims: Myocardial stretch increases cardiac force in two consecutive phases: The first one due to Frank-Starling mechanism, followed by the gradually developed slow force response (SFR). The latter is the mechanical ...
Genome-scale comparative analysis for host resistance against sea lice between Atlantic salmon and rainbow trout
(2021-12-01)
Sea lice (Caligus rogercresseyi) is an ectoparasite which causes major production losses in the salmon aquaculture industry worldwide. Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) are two of the ...
Transcriptional analysis of THP-1 cells infected with leishmania infantum indicates no activation of the inflammasome platform
(2020-01-01)
Leishmaniasis is caused by intracellular parasites transmitted to vertebrates by sandfly bites. Clinical manifestations include cutaneous, mucosal or visceral involvement depending upon the host immune response and the ...
Genome‑scale comparative analysis for host Resistance against sea lice between Atlantic salmon and rainbow trout
(Nature Research, Germany, 2021)
Sea lice (Caligus rogercresseyi) is an ectoparasite which causes major production losses in the salmon
aquaculture industry worldwide. Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus
mykiss) are two of the ...
Genes candidatos para características de crescimento, reprodução e resistência em bovinos de corte
(Universidade Federal de Minas GeraisBrasilVET - DEPARTAMENTO DE ZOOTECNIACurso de Graduação em ZootecniaUFMG, 2020-06-30)
Selecting animals which have favorable alleles in genes that participate in the genetic control
of economic interest traits may increase the efficiency of beef cattle breeding programs. In this
way, two papers were ...
Análise em larga escala da senescência desencadeada por FGF-2 em células tumorais de camundongo da linhagem Y1
(Universidade Federal de São Paulo (UNIFESP), 2019-08-29)
Despite being a growth factor, FGF-2 has anti-proliferative and tumor suppressive functions in some cellular contexts. In a murine adrenocortical tumor cell line that has the proto-oncogene K-Ras constitutively amplified ...