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Network pharmacology reveals multitarget mechanism of action of drugs to be repurposed for COVID-19
(Frontiers Media S.A., 2024)
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?
(Smart Science & Technology, 2014-02)
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of ...
Computational prediction of protein-protein interactions in Leishmania predicted proteomes
(Public Library of Science, 2014)
Immunopeptidomic Data Integration to Artificial Neural Networks Enhances Protein-Drug Immunogenicity Prediction
(Frontiers Media S.A., 2020-06)
Recombinant DNA technology has, in the last decades, contributed to a vast expansion of the use of protein drugs as pharmaceutical agents. However, such biological drugs can lead to the formation of anti-drug antibodies ...
Intrinsic disorder associated with 14-3-3 proteins and their partners
(Elsevier, 2019-01)
Protein-protein interactions (PPIs) mediate a variety of cellular processes and form complex networks, where connectivity is achieved owing to the “hub” proteins whose interaction with multiple protein partners is facilitated ...
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV) and 2019 novel
coronavirus (2019-nCoV, also known as SARS-CoV-2), lead global epidemics with high morbidity and mortality.
However, ...