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Heat shock proteins and DNA repair mechanisms: an updated overview
(Springer, 2018-05)
Heat shock proteins (HSPs), also known as molecular chaperones, participate in important cellular processes, such as protein aggregation, disaggregation, folding, and unfolding. HSPs have cytoprotective functions that are ...
Participation of heat shock proteins in DNA repair mechanisms in cancer
(Nova Science Publishers, 2010)
Heat shock proteins (HSPs) are well known as molecular chaperones, playing important roles in cellular metabolism, escorting other proteins during aggregation, disaggregation, folding, and unfolding. They have been classified ...
Crystallographic and calorimetric studies with nuclear transport of DNA repair proteins
(Int Union Crystallography, 2018-08-01)
DNA repair deficiency in neuropathogenesis: when all roads lead to mitochondria
(2019)
Mutations in DNA repair enzymes can cause two neurological clinical manifestations: a developmental impairment and a degenerative disease. Polynucleotide kinase 3′-phosphatase (PNKP) is an enzyme that is actively involved ...
Differential contribution of HP1 proteins to DNA end resection and homology-directed repair
(Taylor & Francis, 2013-02)
Heterochromatin protein 1 paralogs (HP1α, β and γ in mammals) are not only central in heterochromatin organization, but have also been linked to transcriptional activation at euchromatic regions, maintenance of telomere ...
Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
(Medicina Oral S.L., 2018)
Inhibitor of growth 1 (ING1) acts at early steps of multiple DNA repair pathways
(Springer, 2013-04)
ING proteins are tumor suppressors involved in the regulation of gene transcription, cell cycle arrest, apoptosis, and senescence. Here, we show that ING1b expression is upregulated by several DNA-damaging agents, in a ...