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Arsenic-related DNA copy-number alterations in lung squamous cell carcinomas
(Nature, 2010)
BACKGROUND: Lung squamous cell carcinomas (SqCCs) occur at higher rates following arsenic exposure. Somatic DNA copy-number
alterations (CNAs) are understood to be critical drivers in several tumour types. We have assembled ...
A study of adrenocortical tumors in children and adolescents by a comparative genomic hybridization technique
(ELSEVIER SCIENCE INC, 2011)
Adrenocortical tumors (ACT) are rare neoplasms of the adrenal glands accounting for 0.2% of all pediatric cancers. However, the incidence of ACT in South Brazilian children is 10 to 15 times greater than the worldwide ...
Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?
(Oxford University Press, 2014-05-15)
A significant proportion (up to 62) of oral squamous cell carcinomas (OSCCs) may arise from oral potential malignant lesions (OPMLs), such as leukoplakia. Patient outcomes may thus be improved through detection of lesions ...
Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast
(Springer NetherlandsDordrecht, 2014-11-13)
Lymphovascular invasion (LVI) and histologic grade are clinical parameters of high prognostic value in breast cancer and indicate the level of tumor aggressiveness. Many studies have focused on the association of breast ...
Caracterização genômica do Edema de Reinke
(Universidade Estadual Paulista (Unesp), 2017-02-23)
Introdução: o Edema de Reinke (ER) é uma lesão laríngea considerada benigna relacionada ao tabagismo. Dados em literatura relatam associações entre o ER e a detecção de diferentes graus de displasia e carcinoma in situ, ...
Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?
(Oxford University Press, 2014)
Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?
(Oxford University Press, 2014)
An Integrative Genomic and Transcriptomic Analysis Reveals Potential Targets Associated with Cell Proliferation in Uterine Leiomyomas
(2013-03-04)
Background: Uterine Leiomyomas (ULs) are the most common benign tumours affecting women of reproductive age. ULs represent a major problem in public health, as they are the main indication for hysterectomy. Approximately ...
An Integrative Genomic and Transcriptomic Analysis Reveals Potential Targets Associated with Cell Proliferation in Uterine Leiomyomas
(2013-03-04)
Background: Uterine Leiomyomas (ULs) are the most common benign tumours affecting women of reproductive age. ULs represent a major problem in public health, as they are the main indication for hysterectomy. Approximately ...
Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors
(2013-04-01)
Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, ...