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DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477)
(Wiley-liss, Div John Wiley & Sons Inc, 2018-12)
MutLα, a heterodimer consisting of MLH1 and PMS2, is a key player of DNA mismatch repair (MMR), yet little is known about its regulation. In this study, we used mass spectrometry to identify phosphorylated residues within ...
Tolerance of DNA mismatches in dmc1 recombinase-mediated DNA strand exchange
(American Society for Biochemistry and Molecular Biology, 2016-03)
Recombination between homologous chromosomes is required for the faithful meiotic segregation of chromosomes and leads to the generation of genetic diversity. The conserved meiosis-specific Dmc1 recombinase catalyzes ...
Mismatch Repair System Proteins In Oral Benign And Malignant Lesions
(Wiley-BlackwellHoboken, 2017)
Hypermutation in burkholderia cepacia complex is mediated by DNA mismatch repair inactivation and is highly prevalent in cystic fibrosis chronic respiratory infection
(Elsevier Gmbh, 2014-08)
The Burkholderia cepacia complex (Bcc) represents an important group of pathogens involved in long-term lung infection in cystic fibrosis (CF) patients. A positive selection of hypermutators, linked to antimicrobial ...
Epigenetic Regulation Of Dna Repair Machinery In Helicobacter Pylori-induced Gastric Carcinogenesis
(BAISHIDENG PUBLISHING GROUP INCPLEASANTON, 2015)
Alterações fisiológicas causadas pelo arsênio, genotoxidade e importância do mecanismo mismatch repair no reparo do DNA em Arabidopsis thalianaPhysiological changes caused by arsenic, genotoxicity and importance of mismatch repair mechanism in DNA repair in Arabidopsis thaliana
(Universidade Federal de Viçosa, 2017)
Mismatch recognition function of Arabidopsis thaliana MutS-gamma
(Elsevier Science, 2013-02)
Genetic stability depends in part on an efficient DNA lesion recognition and correction by the DNA mismatch repair (MMR) system. In eukaryotes, MMR is initiated by the binding of heterodimeric MutS homologue (MSH) complexes, ...
Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
(Medicina Oral S.L., 2018)
Analysis of DNA structure and sequence requirements for Pseudomonas aeruginosa MutL endonuclease activity
(Oxford University Press, 2013-08)
The hallmark of the mismatch repair system in bacterial and eukaryotic organisms devoid of MutH is the presence of a MutL homologue with endonuclease activity. The aim of this study was to analyse whether different DNA ...
Helicobacter Pylori Infection Modulates The Expression Of Mirnas Associated With Dna Mismatch Repair Pathway
(Wiley-BlackwellHoboken, 2017)