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Síntese translesão e reparo de DNA em Trypanosoma cruzi: caracterização funcional da DNA polimerase kappa e análise da remoção de lesões no DNA nuclear e mitocondrial
(Universidade Federal de Minas GeraisUFMG, 2011-04-27)
Trypanosoma cruzi is the causative agent of Chagas disease, and during its life cycle it is subjective to several genotoxic agents, which can lead to mutations, cell division blockage or even cell death. The major mechanisms ...
Avaliação da importância do fotorreparo de DNA em anfíbios
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2019-02-19)
Amphibians have suffered a widespread population decline across the globe. About 40% of existing amphibian species are threatened with extinction. Solar ultraviolet (UV) radiation (280-400 nm) has the capacity to form ...
Variação da concentração de ozônio e efeitos genotóxicos da radiação UV no sul do Brasil
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2022-08-26)
Decreases in stratospheric ozone concentration over the last 40 years influenced by the Antarctic ozone hole have altered the incidence levels of solar ultraviolet (UV) radiation in the south of the Southern Hemisphere. ...
Real-time PCR assay for detection and quantification of Leishmania (Viannia) organisms in skin and mucosal lesions: Exploratory study of parasite load and clinical parameters
(American Society for Microbiology, 2013)
Earlier histopathology studies suggest that parasite loads may differ between cutaneous leishmaniasis (CL) and mucosal leishmaniasis (ML) lesions and between acute and chronic CL. Formal demonstration requires highly ...
p16INK4A immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus
(2003-10-01)
Human papillomavirus (HPV) is believed to promote the oncogenic process, and the correlation between viral oncoproteins and dysfunction of p16 INK4A tumor suppressor protein in oral lesions is controversial. To test the ...
p16INK4A immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus
(2003-10-01)
Human papillomavirus (HPV) is believed to promote the oncogenic process, and the correlation between viral oncoproteins and dysfunction of p16 INK4A tumor suppressor protein in oral lesions is controversial. To test the ...
The genotoxic effects of DNA lesions induced by artificial UV-radiation and sunlight
(ELSEVIER SCIENCE SA, 2010)
Solar radiation sustains and affects all life forms on Earth. The increase in solar UV-radiation at environmental levels, due to depletion of the stratospheric ozone layer, highlights serious issues of social concern. This ...
Mate attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus
(Pergamon-Elsevier B.V. Ltd, 2009-07-01)
Drinking hot mate has been associated with risk for esophageal cancer in South America. Thus. the aims of this study were to evaluate the modifying effects of mate intake on DNA damage and esophageal carcinogenesis induced ...
Mate attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus
(Pergamon-Elsevier B.V. Ltd, 2009-07-01)
Drinking hot mate has been associated with risk for esophageal cancer in South America. Thus. the aims of this study were to evaluate the modifying effects of mate intake on DNA damage and esophageal carcinogenesis induced ...