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Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist
(Elsevier B.V., 2005-11-01)
In epileptic patients, there is a high incidence of psychiatric comorbidities, such as anxiety. Gamma-aminobutyric acid (GABA) ionotropic receptor GABA(A)/benzodiazepine allosteric site is involved in both epilepsy and ...
Relationship between thresholds to convulsions induced by a benzodiazepine inverse agonist and [H-3]-L-glutamate binding in the membranes of brain regions
(Springer, 2013-04-01)
Although some studies have investigated the influence of kindling model of epilepsy on the glutamatergic neurotransmission, the relation between glutamatergic receptors and seizure susceptibility remains unclear. the present ...
Análise comportamental de ratos susceptíveis e nao susceptíveis as convulsões clônicas induzidas pelo DMCM, um agonista inverso benzodiazepínico
(Universidade Federal de São Paulo (UNIFESP), 2004)
Há evidências clínicas e farmacológicas que sugerem uma deficiência na neurotransmissão GABAérgica, mediada pelo receptor GABAR/BZD, nas epilepsias e nas desordens psiquiátricas das ansiedades e das depressões. O objetivo ...
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: Evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test
(Elsevier B.V., 2009-04-24)
Previous studies have demonstrated that microinjections of midazolam, a benzodiazepine receptor agonist, into the amygdala produce anxiolytic-like effects in elevated plus-maze (EPM)-naive rodents. However, systemic or ...
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: Evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test
(Elsevier B.V., 2009-04-24)
Previous studies have demonstrated that microinjections of midazolam, a benzodiazepine receptor agonist, into the amygdala produce anxiolytic-like effects in elevated plus-maze (EPM)-naive rodents. However, systemic or ...
Estudo farmacológico e auto-radiográfico do complexo GABAA/Sítio benzodiazepínico, e ensaios bioquímicos da enzima Na+/K+- Atpase e de receptores glutamatérgicos em regiões encefálicas de ratos susceptíveis e não-susceptíveis às convulsões clônicas induzidas pelo DMCM, um agonista inverso benzodiazepínico
(Universidade Federal de São Paulo (UNIFESP), 2008-12-26)
Objective: The aim of this work was to verify if rats susceptible and non-susceptible to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist, differ: 1) in the sensitivity to the hypnotic effect induced ...
Ultrasonographic cervical evaluation: A tool to select ewes for non-surgical embryo recovery
(Wiley-Blackwell, 2020-10-29)
This study assessed the cervical ultrasonography mapping as a tool to select donor ewes for non-surgical embryo recovery (NSER). Lacaune ewes had their cervix evaluated by ultrasonography 12 hr after induced oestrus onset ...