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Avaliar o efeito do receptor P2X 7 no sistema renina- angiotensina durante a progressão da nefropatia diabética
(Universidade Federal de São Paulo (UNIFESP), 2020-01-30)
Aim: To analyze the effect of P2X7 receptor on RAS in DN. Methods: Uninephectomized male Wistar rats received a single dose of streptozotocin (60 mg/kg, i.v) for diabetes mellitus (DM) induction; control animals (CTL) ...
Estructura 3D de péptidos con potencial actividad Leishmanicida
(2015-01-26)
Resumen: En este trabajo se sintetizaron 7 péptidos llamados DM 1.1, DM 1.2, DM 1.3, DM 1.4 DM 1.5, DM 1.6 y DM1.7 análogos de DM 1 (ALWKTMLKKLGTMAL). DM 1 es un derivado de la dermaseptina S1 (ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ), ...
Rutin administration attenuates myocardial dysfunction in diabetic rats
(BioMed Central, 2015)
Oxidative stress plays a major role in diabetic cardiomyopathy pathogenesis. Anti-oxidant therapy has been investigated in preventing or treating several diabetic complications. However, anti-oxidant action on diabetic-induced ...
Low intensity physical exercise attenuates cardiac remodeling and myocardial oxidative stress and dysfunction in diabetic rats
(2015)
We evaluated the effects of a low intensity aerobic exercise protocol on cardiac remodeling and myocardial function in diabetic rats. Wistar rats were assigned into four groups: sedentary control (C-Sed), exercised control ...
Heterologous expression of the antimyotoxic protein DM64 in Pichia pastoris
(Public Library of Science, 2018)
Novas raças de Bremia lactucae, agente causador do míldio da alface, identificadas no estado de São Paulo
(Associação Brasileira de Horticultura, 2011-09-01)
O objetivo deste trabalho foi relatar o surgimento de raças de Bremia lactucae, agente causal do míldio nas principais regiões produtoras de alface do estado de São Paulo. O estudo foi realizado no Laboratório de Melhoramento ...
Novas raças de Bremia lactucae, agente causador do míldio da alface, identificadas no estado de São Paulo
(Associação Brasileira de Horticultura, 2011-09-01)
O objetivo deste trabalho foi relatar o surgimento de raças de Bremia lactucae, agente causal do míldio nas principais regiões produtoras de alface do estado de São Paulo. O estudo foi realizado no Laboratório de Melhoramento ...
DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment
(SPRINGERDORDRECHT, 2013-08-02)
This paper describes a new method for the preparation of sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate, DM-1, and 3-oxo-penta-1,4-dienyl-bis (2-methoxy-phenolate), DM-2. The aim of ...
Searching for TeV DM evidence from Dwarf Irregular Galaxies with the HAWC Observatory
(2017-01-01)
The dynamics of dwarf irregular (dIrr) galaxies are observed to be dominated by dark matter (DM). Recently, the DM density distribution has been studied for 31 dIrrs. Their extended DM halo (Burket type profile) makes these ...