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Cystathionine γ-lyase, an Enzyme Related to the Reverse Transsulfuration Pathway, is Functional in Leishmania spp.
(Wiley Blackwell Publishing, Inc, 2014-03)
Leishmania parasites seem capable of producing cysteine by de novo biosynthesis, similarly to bacteria, some pathogenic protists, and plants. In Leishmania spp., cysteine synthase (CS) and cystathionine β-synthase (CBS) ...
Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage
(OXFORD UNIV PRESS, 2011)
Background. Cisplatin (CP)-induced renal damage is associated with inflammation. Hydrogen sulphide (H(2)S) is involved in models of inflammation. This study evaluates the effect of DL-propargylglycine (PAG), an inhibitor ...
Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage
(Oxford Univ Press, 2011-02-01)
Background. Cisplatin (CP)-induced renal damage is associated with inflammation. Hydrogen sulphide (H(2)S) is involved in models of inflammation. This study evaluates the effect of DL-propargylglycine (PAG), an inhibitor ...
Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin
(Associação Brasileira de Divulgação Científica, 2012)
Animal models of gentamicin nephrotoxicity present acute tubular necrosis associated with inflammation, which can contribute to intensify the renal damage. Hydrogen sulfide (H2S) is a signaling molecule involved in ...
Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
Background and purpose: Recent findings suggest that the noxious gas H(2)S is produced endogenously, and that physiological concentrations of H(2)S are able to modulate pain and inflammation in rodents. This study was ...
Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: Role of ATP-sensitive potassium channels
(AMER ASSOC IMMUNOLOGISTS, 2008)
In this study, we have addressed the role of H2S in modulating neutrophil migration in either innate (LPS-challenged naive mice) or adaptive (methylated BSA (mBSA)-challenged immunized mice) immune responses. Treatment of ...
Hydrogen Sulfide Improves Neutrophil Migration and Survival in Sepsis via K(ATP)(+) Channel Activation
(AMER THORACIC SOC, 2010)
Rationale Recovering the neutrophil migration to the infectious focus improves survival in severe sepsis. Recently, we demonstrated that the cystathionine gamma-lyase (CSE)/hydrogen sulfide (H(2)S) pathway increased ...
Efeitos farmacológicos do extrato etanólico das cascas do fruto de Nephelium lappaceum L. na nocicepção e na úlcera gástricaPharmacological effects of the ethanolic extract of the fruit peels of Nephelium lappaceum L. on nociception and gastric ulcer
(Pós-Graduação em Ciências da SaúdeUniversidade Federal de Sergipe, 2022)
Efeitos gastroprotetores do timol em úlceras agudas e crônicas em ratos : evidências do envolvimento das prostaglandinas, canais para potássio sensíveis a ATP e secreção do muco gástricoGastroprotective effects of thymol on acute and chronic ulcers in rats: evidence involment of prostaglandins, ATP-sensitive K+ channels, and gastric mucus secretion
(Universidade Federal de SergipePós-Graduação em Ciências FisiológicasBrasilUFS, 2017)