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Molecular modeling study on the disassembly of dendrimers designed as potential antichagasic and antileishmanial prodrugs
(Springer, 2012-05-01)
A molecular modeling study was carried out to investigate the most likely enzymatic disassembly mechanism of dendrimers that were designed as potential antichagasic and antileishmanial prodrugs. the models contained ...
Evaluation of biofilm-forming capacity of Moraxella bovis, the primary causative agent of infectious bovine keratoconjunctivitis
(Elsevier Science, 2013-10)
The difficulties in preventing and treating infectious bovine keratoconjunctivitis (IBK) and the consequent impact on the cattle industry worldwide emphasize the need to better understand this infectious process along with ...
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly
(2019-04-29)
The permeability of endothelial cells is regulated by the stability of the adherens junctions, which is highly sensitive to kinase-mediated phosphorylation and endothelial nitric oxide synthase (eNOS)-mediated S-nitrosylation ...
Targeting stress granules: A novel therapeutic strategy for human diseases
Stress granules (SGs) are assemblies of mRNA and proteins that form from mRNAs
stalled in translation initiation in response to stress. Chronic stress might even induce
formation of cytotoxic pathological SGs. SGs ...
Métodos de limpeza de equipamentos industriais: destaque para o sistema CIP
(Universidade Federal de São CarlosUFSCarCâmpus São CarlosEngenharia Química - EQ, 2023-03-14)
In recent years, sanitaries demands to the production process and the final product, both by government and by consumers, have been growing more and more. One of the requirements, which makes the production and, consequently, ...
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly
(Facultad de Medicina y CienciaCentro de Biología Celular y Biomedicina CEBICEM, 2019)
The permeability of endothelial cells is regulated by the stability of the adherens junctions, which is highly sensitive to kinase-mediated phosphorylation and endothelial nitric oxide synthase (eNOS)-mediated S-nitrosylation ...
Redox-active polyamine-salt aggregates as multistimuli-responsive soft nanoparticles
(Royal Society of Chemistry, 2020-03-13)
Polyamine-salt aggregates have become promising soft materials in nanotechnology due to their easy preparation process and pH-responsiveness. Here, we report the use of hexacyanoferrate(II) and hexacyanoferrate(III) as ...
Characterization of anti-silencing factor 1 in Leishmania major
(FUNDACO OSWALDO CRUZRIO DE JANEIRO, 2012)
Anti-silencing factor 1 (ASF1) is a histone chaperone that contributes to the histone deposition during nucleosome assembly in newly replicated DNA. It is involved in chromatin disassembly, transcription activation and in ...