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Downregulation of L-arginine metabolism in dendritic cells induces tolerance to exogenous antigen
(2017-03-01)
Dendritic cells (DC) are potential tools for therapeutic applications and several strategies to generate tolerogenic DCs are under investigation. When activated by cytokines and microbial products, DCs express mediators ...
Dendritic cell maturation and cross-presentation: timing matters!
(Wiley Blackwell Publishing, Inc, 2016-07)
As a population, dendritic cells (DCs) appear to be the best cross-presenters of internalized antigens on major histocompatibility complex class I molecules in the mouse. To do this, DCs have developed a number of unique ...