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Atas de Registro de Preços
(2013)
DCL
(2013)
Induced folding in RNA recognition by Arabidopsis thaliana DCL1
(Oxford University Press, 2015-06)
DCL1 is the ribonuclease that carries out miRNA biogenesis in plants. The enzyme has two tandem double stranded RNA binding domains (dsRBDs) in its C-terminus. Here we show that the first of these domains binds precursor ...
Especificação modular de restrições arquiteturais
(Universidade Federal de Minas GeraisUFMG, 2016-06-03)
After years of continuous evolution, it is usual to observe misalignments between code and architecture, leading to a phenomenon known as architectural erosion. DCL (Dependency Constraint Language) is a domain-specific ...
The key role of electrostatic interactions in the induced folding in RNA recognition by DCL1-A
(Royal Society of Chemistry, 2018-03)
The intrinsically disordered protein domain DCL1-A is the first report of a complete double stranded RNA binding domain folding upon binding. DCL1-A recognizes the dsRNA by acquiring a well-folded structure after engagement ...