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Distribution of alleles of DRD4 and DAT1 genes of the dopaminergic system in the mixed Chilean population Distribución de alelos de los genes DRD4 y DAT1 del sistema dopaminérgico en la población mixta de Santiago de Chile
(2003)
Background: Genes for dopamine receptor DRD4 and dopamine transporter DAT1 are highly polymorphic. Two alleles of these genes, namely the DRD4.7 and the DAT1*9 are frequently associated to the attention deficit disorder ...
Distribución de alelos de los genes DRD4 y DAT1 del sistema dopaminérgico en la población mixta de Santiago de Chile
(Sociedad Médica de Santiago, 2003)
A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants
(ELSEVIER SCIENCE BV, 2011)
The trematode Schistosoma mansoni is the primary cause of schistosomiasis, a devastating neglected tropical disease that affects 200 million individuals. Identifying novel therapeutic targets for the treatment of schistosomiasis ...
Genotypic interaction between DRD4 and DAT1 loci is a high risk factor for attention-deficit/hyperactivity disorder in Chilean families
(WILEY, 2006)
Attention-deficit/hyperactivity disorder, ADHD [MIM 126452], is a common, highly heritable neurobiological disorder of childhood onset, characterized by hyperactivity, impulsiveness, and/or inattentiveness. As part of an ...
Molecular genetic case-control women investigation from the first Brazilian high-risk study on functional psychosis
(Associação Brasileira de Psiquiatria - ABP, 2008)
OBJECTIVE: Data from epidemiological studies have demonstrated that genetics is an important risk factor for psychosis. The present study is part of a larger project, pioneer in Brazil, which has been conducted by other ...
Evidence of an association between 10/10 genotype of DAT1 and endophenotypes of attention deficit/hyperactivity disorder
(2015)
Introduction: Genetic variance of attention deficit-hyperactivity disorder (ADHD) is a strong determinant of this disorder. The 40 base pairs (bp) variable number tandem repeat (VNTR) located in the 3' untranslated region ...
Distribution of alleles of drd4 and dat1 genes of the dopaminergic system in the mixed chilean population
(SOCIEDAD MEDICA DE SANTIAGO, 2003)
Molecular Imaging Genetics of Methylphenidate Response in ADHD and Substance Use Comorbidity
(Wiley-Blackwell, 2011-02-01)
Purpose: Attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs) are highly comorbid and may share a genetic vulnerability. Methylphenidate (MPH), a dopamine transporter (DAT) blocker, is an ...
Asociación de polimorfismos funcionales en genes candidatos DAT1 Y DRD4, y características neuropsicológicas en atención y funciones ejecutivas en población de niños, niñas y adolescentes con diagnóstico de déficit de atención e hiperactividad, del centro de Colombia
(2012)
El Trastorno por déficit de atención e Hiperactividad (TDAH), es un cuadro diagnóstico y clínicamente heterogéneo. Se buscó analizar la asociación de polimorfismos funcionales en genes candidatos DAT1 VNTR 3´ UTR y DRD4 ...
Combinación de genotipos DRD4 y DAT1 constituye importante factor de riesgo en miembros de familias de Santiago de Chile con déficit atencional
(SOC MEDICA SANTIAGO, 2008-06)
Background: Attention deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurobiological disorder of childhood onset, characterized by hyperactivity, impulsiveness, and/or inattentiveness. Aim: To search ...