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White dwarf cooling by means of heat waves
(ASP Astronomical Society of the Pacific, 2005-06)
The standard white dwarf (WD) cooling theory is revised when the heat flux is propagate by thermal waves in degenerate material. Before the relaxation time, the luminosity function is dampening oscillation and the WD-age increase.
Impact of dampening demand variability in a production/inventory system with multiple retailers
We study a supply chain consisting of a single manufacturer and two retailers. The manufacturer produces goods on a make-to-order basis, while both retailers maintain an inventory and use a periodic replenishment rule. As ...
The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide binds to toll-like receptor-2-TIR-BB-loop domain and dampens downstream inflammatory signaling
(Elsevier Science, 2019-06-01)
The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide (DMPO) dampens endotoxin-induced and TLR4-driven priming of macrophages, but the mechanism remains unknown. The available information suggests a direct binding of DMPO ...
Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal–fetal infammation in mice
(2022)
Background: One of every four preterm neonates is born to a woman with sterile intra-amniotic inflammation (inflammatory process induced by alarmins); yet, this clinical condition still lacks treatment. Herein, we utilized ...
Circadian rhythms of locomotor activity and hippocampal clock genes expression are dampened in vitamin A-deficient rats
(Elsevier Inc, 2014-04)
The main external time giver is the day-night cycle; however, signals from feeding and the activity/rest cycles can entrain peripheral clocks, such as the hippocampus, in the absence of light. Knowing that vitamin A and ...
Daily oscillation of glutathione redox cycle is dampened in the nutritional vitamin A deficiency
(Taylor & Francis Ltd, 2012-08)
Examples of hormonal phase-shifting of circadian gene expression began to emerge a few years ago. Vitamin A fulfills a hormonal function by binding of retinoic acid to its nuclear receptors, RARs and RXRs. We found retinoid- ...
The nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide dampens lipopolysaccharide-induced transcriptomic changes in macrophages
(Birkhauser Verlag Ag, 2018-06)
Objective: M1-like inflammatory phenotype of macrophages plays a critical role in tissue damage in chronic inflammatory diseases. Previously, we found that the nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) ...