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Poloxamer-based binary hydrogels for delivering tramadol hydrochloride: sol-gel transition studies, dissolution-release kinetics, in vitro toxicity, and pharmacological evaluation
(Dove Medical Press Ltd, 2015-01-01)
In this work, poloxamer (PL)-based binary hydrogels, composed of PL 407 and PL 188, were studied with regard to the physicochemical aspects of sol-gel transition and pharmaceutical formulation issues such as dissolution-release ...
Desenvolvimento e validação de método por cromatografia líquida em fase reversa para análise de febuxostate
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2013-07-25)
Febuxostat is a novel non purine drug indicated for the treatment of hyperuricemia in gout. A reversed-phase liquid chromatography (RP-LC) method was validated for the determination of febuxostat in pharmaceutical dosage ...
Desenvolvimento de Método Indicativo da Estabilidade, Ensaio de Dissolução e Estudo Preliminar da Estabilidade e Citotoxicidade do Ciprofibrato em Formas FarmacêuticasDevelopment of a stability-indicating method, dissolution assay and preliminary study of ciprofibrate stability and citotoxicity in pharmaceutical formulations
(Universidade Federal do PampaCampus Uruguaiana, 2015)
Avaliação da capacidade de limpeza e biocompatibilidade de diferentes soluções irrigadoras utilizadas em Endodontia
(Universidade Estadual Paulista (Unesp), 2018-12-17)
Os objetivos deste estudo foram: Artigo 1 – Analisar a extrusão apical de hipoclorito de sódio (NaOCl), debris e sua citotoxicidade após o preparo dos canais radiculares utilizando NaOCl líquido ou gel. Artigo 2- avaliar ...
Pluronics F-127/L-81 Binary Hydrogels as Drug-Delivery Systems: Influence of Physicochemical Aspects on Release Kinetics and Cytotoxicity
(Amer Chemical Soc, 2014-11-18)
We investigated the structure of the binary mixture of Pluronic F-127 (PL F-127) and Pluronic L-81 (PL L-81), as hydrogels for sumatriptan delivery and investigated the mixture possible use via subcutaneous route for future ...