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In Vitro interaction of poliovirus with cytoplasmic dynein
(Intervirology, 2007-02-02)
Objective: Poliovirus (PV) enters the host by the oral route and can infect the central nervous system (CNS) by two mechanisms: crossing the blood-brain barrier and traveling along the nerves from the muscle to the spinal ...
Dynein and kinesin regulate stress granule and P-body dynamics
(Company of Biologists, 2009-11)
Stress granules (SGs) and P-bodies (PBs) are related cytoplasmic structures harboring silenced mRNAs. SGs assemble transiently upon cellular stress, whereas PBs are constitutive and are further induced by stress. Both foci ...
Characterization of the human dynein light chain Rp3 and its use as a non-viral gene delivery vector
(SpringerNew YorkEUA, 2014)
Cyclophilin-A is bound to through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex
(American Society for Biochemistry and Molecular Biology, 2004-10-20)
Although cyclophilin A (CyP-A) is a relatively abundant small immunophilin present in the cytoplasm of all mammalian cells, its general function(s) in the absence of the immunosuppressant drug cyclosporin A is not known. ...
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus
(American Society for Biochemistry and Molecular Biology, 2004)
The tumor suppressor protein p53 is known to be transported to the nucleus along microtubular tracks by cytoplasmic dynein. However, the connection between p53 and the dynein motor protein complex has not been established. ...
Development of a non-viral gene delivery vector based on the dynein light chain Rp3 and the TAT peptide
(Elsevier Science BvAmsterdamHolanda, 2014)
Evidence for glucocorticoid receptor transport on microtubules by dynein
(American Society for Biochemistry and Molecular Biology, 2004)
Rapid, ligand-dependent movement of glucocorticoid receptors (GR) from cytoplasm to the nucleus is hsp90-dependent, and much of the movement system has been defined. GR.hsp90 heterocomplexes isolated from cells contain one ...
Asymmetries in kinesin-2 and cytoplasmic dynein contributions to melanosome transport
(Elsevier Science, 2015-07)
The mechanisms involved in bidirectional transport along microtubules remain largely unknown. We explored the collective action of kinesin-2 and dynein motors during transport of melanosomes in Xenopus laevis melanophores. ...
Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization
(Amer Soc Cell
Biology, 2015)
ABSTRACT Kinesin-5 is a slow homotetrameric motor protein best known for its essential role in the mitotic spindle, where it limits the rate at which faster motors can move microtubules. In neurons, experimental suppression ...