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The carotid body detects circulating tumor necrosis factor-alpha to activate a sympathetic anti-inflammatory reflex
(2022-05-01)
Recent evidence has suggested that the carotid bodies might act as immunological sensors, detecting pro-inflammatory mediators and signalling to the central nervous system, which, in turn, orchestrates autonomic responses. ...
The sympathetic nervous system affects the susceptibility and course of Trypanosoma cruzi infection
(Academic Press Inc Elsevier Science, 2016-11)
Trypanosoma cruzi (T. cruzi) is an intracellular parasite that causes Chagas’ disease, a major health problem in Latin America. Using a murine model of infection with this parasite, we have previously shown that corticosterone ...
Cardiovascular autonomic neuropathy in diabetes: Pathophysiology, clinical assessment and implications
(Baishideng Publishing Group, 2021)
Editorial: Carotid body: A new target for rescuing neural control of cardiorespiratory balance in disease
(Frontiers Research Foundation, 2015)
Pro-inflammatory cytokines and painCitocinas pró-inflamatórias e dor
(2006-01-01)
This review aims to describe the interaction between cytokines, glial cells and pain mechanism. Humans can identify an aggressive stimulus and memorize it for their own defense to face new threats through a withdrawal motor ...
Cytokines: Sensors of the nervous system
(2012)
The central nervous system (CNS) and the immune system share multiple chemical messengers ranging from small molecules, such as corticotropin-releasing factor (CRF) to large proteins, such as cytokines and growth factors. ...
Cytokines: Sensors of the nervous system
(2012)
The central nervous system (CNS) and the immune system share multiple chemical messengers ranging from small molecules, such as corticotropin-releasing factor (CRF) to large proteins, such as cytokines and growth factors. ...
Adaptations in autonomic function during exercise training in heart failure
(SPRINGER, 2008)
Although neurohumoral excitation is the hallmark of heart failure (HF), the mechanisms underlying this alteration are not entirely known. Abnormalities in several systems contribute to neurohumoral excitation in HF, including ...
Alterações cardiovasculares induzidas pela obesidade : envolvimento do sistema reninaangiotensina no núcleo do trato solitário
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2016-02-01)
In the last decades, obesity has become a worldwide epidemy. Excess of adipose tissue favors the development of associated diseases such as hypertension, obstructive sleep apnea and type II diabetes. Data from the literature ...
Neural reflex regulation of systemic inflammation: potential new targets for sepsis therapy
(Frontiers Research Foundation, 2014)
Sepsis progresses to multiple organ dysfunction due to the uncontrolled release of inflammatory mediators, and a growing body of evidence shows that neural signals play a significant role in modulating the immune response. ...