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Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery
(Springer Heidelberg, 2014-12)
The binding of peptides to classical major histocompatibility complex (MHC) class I proteins is the single most selective step in antigen presentation. However, the peptide-binding specificity of cattle MHC (bovine leucocyte ...
Protective CD8+ T Cell Responses against the Pre-erythrocytic Stages of Malaria Parasites: an Overview
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Computational comparison of availability in CTL/gag epitopes among patients with acute and chronic HIV-1 infection
(Elsevier, 2018-06-27)
Background: Recent studies indicate that there is selection bias for transmission of viral polymorphisms associated with higher viral fitness. Furthermore, after transmission and before a specific immune response is mounted ...
Determination of common HIV-1 cytotoxic T lymphocytes epitopes across different ethnicities for their potencial use as immunological therapy in Colombia.
(Universidad de AntioquiaMedellín: Universidad de Antioquia, 2021, 2021)
Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle
(BioMed Central, 2014-04)
Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on ...
Polymorphism of the Human Immunodeficiency Virus Type 1 in Brazil: Genetic Characterization of the nef Gene and Implications for Vaccine Design
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens
(Frontiers Media, 2022)
Clostridium perfringens is a dangerous bacterium and known biological warfare weapon associated with several diseases, whose lethal toxins can produce necrosis in humans. However, there is no safe and fully effective vaccine ...
Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment
(Wiley, 2014)
Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in silico Methods: have been developed to ...