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Biophysical and pharmacological characterization of a full-length synthetic analog of the antitumor polypeptide crotamine
(2020-01-01)
Abstract: Crotamine is a polypeptide isolated from the venom of a South American rattlesnake. Among the properties and biological activities of crotamine, the most extraordinary is its ability to enter cells with unique ...
Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Crotamine, one of the main toxic components of Crotalus durissus terrificus venom, is a small non-enzymatic basic polypeptide, which causes hind limb paralysis and necrosis of muscle cells. it is well-known that several ...
Distribution of I-125-labeled crotamine in mice tissues
(Elsevier B.V., 2006-10-01)
Crotamine is a strong basic polypeptide from Crotalus durissus terrificus (Cdt) venom composed of 42 amino acid residues tightly bound by three disulfide bonds. It causes skeletal muscle spasms leading to spastic paralysis ...
Distribution of I-125-labeled crotamine in mice tissues
(Elsevier B.V., 2006-10-01)
Crotamine is a strong basic polypeptide from Crotalus durissus terrificus (Cdt) venom composed of 42 amino acid residues tightly bound by three disulfide bonds. It causes skeletal muscle spasms leading to spastic paralysis ...
Evaluation of the in vitro antitumor effect of the association between doxorubicin and crotamine toxinAssessment of the in vitro antitumor effect of the association between doxorubicin and crotamine toxin
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
Automated NMR structure determination and disulfide bond identification of the myotoxin crotamine from Crotalus durissus terrificus
(Elsevier B.V., 2005-12-01)
Crotamine is one of four major components of the venom of the South American rattlesnake Crotalus durissus terrificus. Similar to its counterparts in the family of the myotoxins, it induces myonecrosis of skeletal muscle ...
Effects of 60Co gamma radiation on crotamine
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-12-01)
Ionizing radiation can change the molecular structure and affect the biological properties of biomolecules. This has been employed to attenuate animal toxins. Crotamine is a strongly basic polypeptide (pI 10.3) from Crotalus ...
Automated NMR structure determination and disulfide bond identification of the myotoxin crotamine from Crotalus durissus terrificus
(Elsevier B.V., 2005-12-01)
Crotamine is one of four major components of the venom of the South American rattlesnake Crotalus durissus terrificus. Similar to its counterparts in the family of the myotoxins, it induces myonecrosis of skeletal muscle ...
Effects of 60Co gamma radiation on crotamine
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-12-01)
Ionizing radiation can change the molecular structure and affect the biological properties of biomolecules. This has been employed to attenuate animal toxins. Crotamine is a strongly basic polypeptide (pI 10.3) from Crotalus ...
Distribution of I-125-labeled crotamine in mice tissues
(Elsevier B.V., 2014)