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Modern drug discovery technologies: opportunities and challenges in lead discovery
(Bentham ScienceBussum, 2011-12)
The identification of promising hits and the generation of high quality leads are crucial steps in the early stages of drug discovery projects. The definition and assessment of both chemical and biological space have ...
The discovery/justification context dichotomy within formal and computational models of scientific theories: a weakening of the distinction based on the perspective of non-monotonic logics
(2017-03-27)
The present paper analyses the topic of scientific discovery and the problem of the existence of a logical framework involved in such endeavour. We inquire how several non-monotonic logic frameworks and other formalisms ...
The discovery/justification context dichotomy within formal and computational models of scientific theories: a weakening of the distinction based on the perspective of non-monotonic logics
(2017-03-27)
The present paper analyses the topic of scientific discovery and the problem of the existence of a logical framework involved in such endeavour. We inquire how several non-monotonic logic frameworks and other formalisms ...
Discovery by Serendipity: a new context for an old riddle
(2015-02-09)
In the last years there has been a great improvement in the
development of computational methods for combinatorial chemistry applied to
drug discovery. This approach to drug discovery is sometimes called a “rational
way” ...
Learning Markov Network Structures Constrained by Context-Specific Independences
(World Scientific, 2014-12)
This work focuses on learning the structure of Markov networks from data. Markov networks are parametric models for compactly representing complex probability distributions. These models are composed by: a structure and ...
Inductive learning strategies in the context of grammar-based teaching
(Universidad Alberto Hurtado, 2018)
BioPlat: a software for human cancer biomarker discovery
(Oxford University Press, 2014-02)
Development of effective tools such as oligo-microarrays and next-generation sequencing methods for monitoring gene expression on a large scale has resulted in the discovery of gene signatures with prognostic/predictive ...
Discovery Tools for Open Access Repositories: Literature Mapping
(2016)
The objective in this paper is to summarize the current knowledge that is available for Discovery Tools that have been employed for library services and open access repositories (OAR); This mapping is intended for studies ...