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Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity
(Springer Verlag Berlín, 2010-10)
Rotenone and pyridaben were tested on activities and properties of rat brain mitochondria determining Ki (inhibitor concentration at half maximal inhibition) and Imax (% of inhibition at maximal inhibitor concentration). ...
Nitric oxide and mitochondria in metabolic syndrome
(Instituto de Histología y Embriología, 2016-04-16)
Normal cardiac function is accomplished through a continuous energy supply provided by mitochondria. Heart mitochondria are the major source of reactive oxygen and nitrogen species: superoxide anion (O2-) and nitric oxide ...
(+)-Catechin inhibits heart mitochondrial complex i and nitric oxide synthase: Functional consequences on membrane potential and hydrogen peroxide production
(Royal Society of Chemistry, 2019-05)
In order to study the in vitro effect of flavan-3-ol (+)-catechin on the enzymatic activities of mitochondrial complex I and nitric oxide synthase (mtNOS), as well as the consequences on the membrane potential and H2O2 ...
Complex i syndrome in myocardial stunning and the effect of adenosine
(Elsevier Science Inc, 2011-09)
Isolated rabbit hearts were exposed to ischemia (I; 15 min) and reperfusion (R; 5-30 min) in a model of stunned myocardium. I/R decreased left-ventricle O 2 consumption (46%) and malate-glutamate-supported mitochondrial ...
Complex I syndrome in myocardial stunning and the effect of adenosine
(Elsevier Science Inc., 2011-09)
Isolated rabbit hearts were exposed to ischemia (I; 15 min) and reperfusion (R; 5-30 min) in a model of stunned myocardium. I/R decreased left-ventricle O 2 consumption (46%) and malate-glutamate-supported mitochondrial ...