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Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms
(2014)
Envenomation by poisonous animals is a neglected condition according to the World Health Organization (WHO). Antivenoms are included in the WHO Essential Medicines List. It has been assumed that immunoglobulin G (IgG) ...
Modulators of complement activation: a patent review (2008 - 2013)
(Informa Healthcare, 2014-03)
Introduction: The architecture of the complement system has evolved during the last 600 – 700 million years to become an amazingly efficient and highly versatile alerting and cell killing device. Under physiological ...
Mannose-binding lectin complement pathway plays a key role in complement activation by Paracoccidioides brasiliensis
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Paracoccidioides brasiliensis (Pb) is a dimorphic fungal pathogen that causes paracoccidioidomycosis the most severe deep mycosis from South America Although cell mediated immunity is considered the most efficient protective ...
Identification of a Novel Mode of Complement Activation on Stimulated Platelets Mediated by Properdin and C3(H2O)
(The American Association of Immunologists, 2013)
Elevated numbers of activated platelets circulate in patients with chronic inflammatory diseases, including atherosclerosis and
coronary disease. Activated platelets can activate the complement system. Although complement ...
Does the complement system work for or against the host during parasite infections
(Research Publisher Inc.Roma, 2013)
Studies regarding the role of the complement system in parasitic infections have demonstrated that the complement system often fails to achieve the intended task of destroying the parasite. The reason for this failure is ...
Structural analysis of effector functions related motifs, complement activation and hemagglutinating activities in Lama glama heavy chain antibodies
(Elsevier Science, 2012-01)
Heavy chain antibodies (HCAbs), devoid of the light chains and the CH 1 domain, are present in the serum of camelids. IgG 2 and IgG 3 are HCAbs; whereas IgG 1 has the conventional structure. In order to study the immunological ...
Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms
(2014)
Envenomation by poisonous animals is a neglected condition according to the World Health Organization (WHO). Antivenoms are included in the WHO Essential Medicines List. It has been assumed that immunoglobulin G (IgG) ...
Trypanosoma cruzi evades the complement system as an efficient strategy to survive in the Mammalian host: the specific roles of host/parasite molecules and Trypanosoma cruzi Calreticulin
(Frontiers media SA, 2017)
American Trypanosomiasis is an important neglected reemerging tropical parasitism,
infecting about 8 million people worldwide. Its agent, Trypanosoma cruzi, exhibits
multiple mechanisms to evade the host immune response ...
Alternative complement pathway and factor B activities in rats with altered blood levels of thyroid hormone
(Associação Brasileira de Divulgação Científica, 2012)
Evaluating the activity of the complement system under conditions of altered thyroid hormone levels might help elucidate the role of complement in triggering autoimmune processes. Here, we investigated alternative pathway ...