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Cochlear synaptopathy: new findings in animal and human research
(Walter de Gruyter GMBH, 2020)
In animal models, prolonged exposure (2 h) to high-level noise causes an irreparable damage to the synapses between the inner hair cells and auditory nerve fibers within the cochlea. Nevertheless, this injury does not ...
The ongoing search for cochlear synaptopathy in humans: Masked thresholds for brief tones in Threshold Equalizing Noise
(Elsevier, 2020)
his study aimed to advance towards a clinical diagnostic method for detection of cochlear synaptopathy with the hypothesis that synaptopathy should be manifested in elevated masked thresholds for brief tones. This hypothesis ...
Preventing presbycusis in mice with enhanced medial olivocochlear feedback
(National Academy of Sciences, 2020)
"Growing old" is the most common cause of hearing loss. Age-related hearing loss (ARHL) (presbycusis) first affects the ability to understand speech in background noise, even when auditory thresholds in quiet are normal. ...
Preventing presbycusis in mice with enhanced medial olivocochlear feedback
(National Academy of Sciences, 2020-05-26)
"Growing old" is the most common cause of hearing loss. Agerelated hearing loss (ARHL) (presbycusis) first affects the ability to understand speech in background noise, even when auditory thresholds in quiet are normal. ...
Reduced suprathreshold auditory nerve responses are associated with slower processing speed and thinner temporal and parietal cortex in presbycusis
(Public Library Science, 2020)
Epidemiological evidence shows an association between hearing loss and dementia in elderly people. However, the mechanisms that connect hearing impairments and cognitive decline are still unknown. Here we propose that a ...
Subclinical hearing loss associated with aging
(Elsevier, 2023)
Objective
Contribute to clarifying the existence of subclinical hearing deficits associated with aging.
Enhancement of the medial olivocochlear system prevents hidden hearing loss
(Society for Neuroscience, 2018-08)
Cochlear synaptopathy produced by exposure to noise levels that cause only transient auditory threshold elevations is a condition that affects many people and is believed to contribute to poor speech discrimination in noisy ...
O papel dos testes eletrofisiológicos no diagnóstico da sinaptopatia coclear
(Universidade Federal de São Paulo (UNIFESP), 2020-08-27)
Objetivo: Avaliar a presença da sinaptopatia coclear em indivíduos normouvintes por meio da aplicação de questionários e a realização de testes eletrofisiológicos auditivos de curta latência, como o Potencial Evocado ...