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Effect of progesterone and first evidence about allopregnanolone action on the progression of epithelial human ovarian cancer cell lines
(Comité editorial Journal of Steroid Biochemistry and Molecular Biology, 2020-02)
ARTÍCULO PUBLICADO EN REVISTA EXTERNA. Ovarian carcinoma is one of the most common cause of death by gynecologic cancer. Several epidemiological and in vitro studies have shown controversial data about progesterone effects ...
HJURP knockdown disrupts clonogenic capacity and increases radiation-induced cell death of glioblastoma cells
(2020-05-01)
The Holliday Junction-Recognition Protein (HJURP) was reported as overexpressed in several cancers and also strongly correlated with poor prognosis of patients, especially in glioblastoma (GBM), the most common and deadly ...
Electrospun Poly(acrylic acid-co-4-styrene sulfonate) as Potential Drug-Eluting Scaffolds for Targeted Chemotherapeutic Delivery Systems on Gastric (AGS) and Breast (MDA-Mb-231) Cancer Cell Lines
(2022)
Abstract: Potential drug-eluting scaffolds of electrospun poly(acrylic acid-co-styrene sulfonate) P(AAco-SS) in clonogenic assays using tumorigenic gastric and ovarian cancer cells were tested in vitro. Electrospun polymer ...
Atypical protein kinase C-ζ modulates clonogenicity, motility, and secretion of proteolytic enzymes in murine mammary cells
(Wiley-liss, div John Wiley & Sons Inc., 2005-01)
In this paper, we investigated whether protein kinase C-ζ (PKCζ), a member of the atypical PKC family, induces phenotypic alterations associated with malignant transformation and tumor progression in mammary cells. The ...
Sistema de conteo automático de colonias de células tumorales
Radiobiology, which studies the effect of radiation-matter interaction in biological systems, is a fundamental area for the optimization of cancer treatment by radiotherapy. One of the most widely used techniques in ...
Sequence dependent exposure of mammary carcinoma cells to Taxotere® and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitro
(Taylor & Francis, 2003-11)
Taxol (paclitaxel) and Taxotere (docetaxel) are considered as two of the most important anticancer chemotherapy drugs. The cytotoxic action of these drugs has been linked to their ability to inhibit microtubule depolymerization, ...
Anticancer activity of 7-epiclusianone, a benzophenone from Garcinia brasiliensis, in glioblastoma
(BioMed Central, 2015)
Abstract
Background
Glioblastoma is the most common tumor of the central nervous system and one of the hardest tumors to treat. Consequently, the search for novel therapeutic ...
Mechanisms enhancing the cytotoxic effects of bleomycin plus suicide or interferon-β gene lipofection in metastatic human melanoma cells
(Bentham Science Publishers, 2018-05)
Background: Three metastatic human melanoma cell lines generated from patient removed lymph nodes and spleen metastasis were established in our laboratory. Objective: To investigate the mechanisms enhancing the cytotoxic ...
The role of single cell derived vascular resident endothelial progenitor cells in the enhancement of vascularization in scaffold-based skin regeneration
(Elsevier, 2011)
Increasing evidence suggests that vascular resident endothelial progenitor cells (VR-EPCs) are present in
several organs, playing an important role in postnatal neovascularization. Here, we isolated and characterized
VR-EPCs ...
Efeitos do silenciamento gênico da enzima quinase MELK sobre a radiossensibilidade de células tumorais prostáticas DU145
(Universidade Estadual Paulista (Unesp), 2021-03-16)
Prostate cancer (PC) is the second type that most kills men when the cause is cancer. Today, there are treatments for the most diverse types of PC, including surgery, radiotherapy, immunotherapy, chemotherapy, and ...