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Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients
(2016)
Gastric cancer (GC) is the third most common cause of cancer death worldwide. Natural killer cells play an important role in the immune defense against transformed cells. They express the activating receptor NKG2D, whose ...
Expression of Protease Activated Receptor-1 in Chronic Periodontitis
(Amer Acad Periodontology, 2014-12-01)
Background: Protease activated receptor-1 (PAR(1)) activation by thrombin may play a role in repair and homeostasis of periodontal tissues. The main objective of this study is to investigate PAR(1) expression in patients ...
Increased fibroblast telomerase expression precedes myofibroblast alpha-smooth muscle actin expression in idiopathic pulmonary fibrosis
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical ...
SEPT10 expression in chronic lymphocytic leukemia. Correlation with clinical and biological prognostic factors
(Scientific Research, 2013-10)
Chronic lymphocytic leukemia (CLL) is characterized by a highly variable clinical course. Microarray studies allowed highlight genes differentially expressed in this pathology. In this study, we have evaluated the prognostic ...
MicroRNA expression in tumors and liquid biopsy samples from patients with pancreatic ductal adenocarcinoma: Identification of clinically relevant pathways
(Amer Assoc Cancer Research, 2018-01-01)
Virulence Factor RNA Transcript Expression in Cultured Clinical Isolates of Leishmania Does Not Vary by Host Age
(Elsevier, 2018)
Background: Virulence factors (VF) are endogenous molecules that often enhance the pathogenicity of an organism. The role of host age on the immunopathogenesis of leishmaniasis is poorly understood. Despite pediatric ...
Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical ...
Expression profile of shelterin components in plasma cell disorders. Clinical significance of POT1 overexpression
(Elsevier, 2014-02)
In this study we analyzed the expression profile and the interactions of all shelterin components in patients with MM and MGUS, and correlated the results with hTERT expression, telomere length (TL) and clinical characteristics ...