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In vivo confocal microscopy study of climatic droplet keratopathy
(Nature Publishing Group, 2012-04)
Climatic droplet keratopathy (CDK) is a corneal degenerative disease characterized by its progressive opacity because of accumulation of globular deposits in Bowman’s layer (BL) and anterior stroma (AS), as well as ...
Climatic droplet keratopathy in Argentina: involvement of environmental agents in its genesis which would open the prospect for new therapeutic interventions
(HINDAWI, 2015-09)
Climatic droplet keratopathy (CDK) is a degenerative corneal disease of unknown etiology. We described CDK for the rst time in Latin America in the Argentinean Patagonia (El Cuy). A deeper knowledge of CDK pathogenic ...
Pro-inflammatory cytokines and gelatinases in climatic droplet keratopathy
(Association for Research in Vision and Ophthalmology, 2012-06)
PURPOSE. Climatic droplet keratopathy (CDK) is a degenerative disease of the cornea with possible involvement from matrix metalloproteinases (MMPs). Therefore, the authors investigated histologic distribution, levels, and ...
Genetic Background and Climatic Droplet Keratopathy Incidence in a Mapuche Population from Argentina
(Public Library Science, 2013-09)
Purpose To determine whether the incidence of and susceptibility to climatic droplet keratopathy (CDK), an acquired, often bilateral degenerative corneal disease, is influenced by the genetic background of the individuals ...
Clinical, Functional and Structural Studies of Humans and Merino Sheep Corneas from Two Different Regions of Argentina
(Wiley Blackwell Publishing, Inc, 2015-11)
Objective: The purpose of our work was to study and compare the cornea and tear film of people and sheep inhabiting in a region of Argentinean Patagonia (PATG), and in a geographically and climatically different region in ...
Phospholipidomic Studies in Human Cornea From Climatic Droplet Keratopathy
(Wiley-liss, Div John Wiley & Sons Inc, 2017-11)
Climatic droplet keratopathy (CDK) is an acquired degenerative disease predominantly affecting males over 40 years old. It results in progressive corneal opacities usually affecting both eyes. CDK is multifactorial and its ...
Estudio del polimorfismo del gen de TNF-α, de dicha citocina, y de MCP-1 en pacientes con queratopatía climática esferoideaStudies of TNF-α gene polymorphism, TNF-α and MCP-1 cytokines in patients with spheroidal climatic keratopathy
(Asociación Argentina de Alergia e Inmunología Clínica, 2013-09)
Objetivo: Investigar polimorfismo de nucleótidos únicos (SNP) en la posición -308 (G/A) del gen TNF-α y la participación de las citocinas TNF-α y MCP-1 en pacientes con queratopatía climática esferoidea (QCE) y en controles ...
Clinical, functional and structural studies of humans and merino sheeps corneas from two different regions of Argentina
(OMICS, 2016-01)
The purpose of our work was to study and compare the cornea and tear film of people and sheep inhabiting in a region of Argentinean Patagonia (PATG), and in a geographically and climatically different region in the Argentinean ...