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Update on Omalizumab for Urticaria: What's New in the Literature from Mechanisms to Clinic
(Current Medicine Group, 2018)
Purpose of Review Since omalizumab has been approved for urticaria, numerous randomized and real-life observational trials have been published. We reviewed the period January 2017 February 2018. Recent Findings Omalizumab ...
Ginecomastia induzida por anti-histamínicos no tratamento da urticária crônica
(Sociedade Brasileira de Dermatologia, 2007-06-01)
Antihistaminic drugs are very commonly used in dermatological practice, and are the first-line therapy to chronic urticaria. The commonest side effects are related to the central nervous system. Gynecomastia, in turn, may ...
Activated status of basophils in chronic urticaria leads to interleukin-3 hyper-responsiveness and enhancement of histamine release induced by anti-IgE stimulus
(BLACKWELL PUBLISHING, 2008)
Background Basophils and mast cells are the main target cells in chronic idiopathic urticaria (CIU). Besides the basopenia, intrinsic defects of the anti-IgE cross-linking signalling pathway of basophils have been described ...
Consensus on the diagnostic and therapeutic management of chronic spontaneous urticaria in adults - Brazilian Society of Dermatology
(Soc Brasileira Dermatologia, 2019-03-01)
BACKGROUND: Urticarias are frequent diseases, with 15% to 20% of the population presenting at least one acute episode in their lifetime. Urticaria are classified in acute (<= 6 weeks) or chronic (> 6 weeks). They may be ...
Increased circulating pro-inflammatory cytokines and imbalanced regulatory T-cell cytokines production in chronic idiopathic urticaria
(ELSEVIER SCIENCE BV, 2008)
The immunologic characterization of chronic idiopathic urticaria (CIU), mainly regarding cytokine profile needs more investigation. We examined circulating inflammatory cytokine levels, T-cell induced secretion, and cytokine ...
Up-regulation of chemokine C-C ligand 2 (CCL2) and C-X-C chemokine 8 (CXCL8) expression by monocytes in chronic idiopathic urticaria
(WILEY-BLACKWELLMALDEN, 2012-01)
The disturbed cytokinechemokine network could play an important role in the onset of diseases with inflammatory processes such as chronic idiopathic urticaria (CIU). Our main objectives were to evaluate the relation between ...
Thyrotropin receptor gene expression in the association between chronic spontaneous urticaria and Hashimoto's thyroiditis
(2017-05-01)
Background: Chronic spontaneous urticaria (CSU) may be associated with autoimmune thyroid diseases, and the Autologous Serum Skin Test (ASST) is an autoreactivity marker. The thyrotropin (TSH) and TSH receptor (TSHR) could ...
Avaliação da relação entre a gravidade da urticária crônica e o impacto na qualidade de vida
(Florianópolis, SC, 2021)