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Discrete typing units of Trypanosoma cruzi detected by real-time PCR in Chilean patients with chronic Chagas cardiomyopathy
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. Chagas disease is a major public health problem in Latin America and has spread to other countries due to immigration of infected persons. 10–30% of patients with chronic Chagas disease will develop ...
Early dystrophin disruption in the pathogenesis of experimental chronic Chagas cardiomyopathy
(ELSEVIER SCIENCE BVAMSTERDAM, 2013-08-02)
Chronic Chagas cardiomyopathy evolves over a long period of time after initial infection by Trypanosoma cruzi. Similarly, a cardiomyopathy appears later in life in muscular dystrophies. This study tested the hypothesis ...
TNF-α and TNFR in Chagas disease: from protective immunity to pathogenesis of chronic cardiomyopathy
(Springer Verlag (Germany), 2018)
Estado actual en el tratamiento de la enfermedad de Chagas
(Sociedad Médica de Santiago, 2011)
Chagas disease cardiomyopathy: current concepts of an old disease
(Instituto de Medicina Tropical, 2008)
Chagas disease continues to be a significant public health problem, as ca. 10 million people are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of individuals can develop a form of ...
Simvastatin attenuates endothelial activation through 15-epi-lipoxin A4 production in murine chronic Chagas cardiomyopathy
(American Society for Microbiology, 2017)
Current treatments for chronic Chagas cardiomyopathy, a disease with
high mortality rates and caused by the protozoan Trypanosoma cruzi, are unsatisfactory.
Myocardial inflammation, including endothelial activation, is ...