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Endothelin-1 and -3 induce choleresis in the rat through ETB receptors coupled to nitric oxide and vagovagal reflexes
(Portland Press Ltd, 2013-06)
We have reported previously that centrally applied ET (endothelin)-1 and ET-3 induce either choleresis or cholestasis depending on the dose. In the present study, we sought to establish the role of these endothelins in the ...
Sandwich-cultured rat hepatocytes as an in vitro model to study canalicular transport alterations in cholestasis
(Springer, 2014-06)
At present, it has not been systematically evaluated whether the functional alterations induced by cholestatic compounds in canalicular transporters involved in bile formation can be reproduced in sandwich-cultured rat ...
ENHANCED BILIARY-EXCRETION OF CANALICULAR MEMBRANE ENZYMES IN ESTROGEN-INDUCED AND OBSTRUCTIVE CHOLESTASIS, AND EFFECTS OF DIFFERENT BILE-ACIDS IN THE ISOLATED-PERFUSED RAT-LIVER
(MUNKSGAARD INT PUBL LTD, 1995)
Backgrounds/Aims: Canalicular membrane enzymes are normally released into bile by partially known processes. This study was undertaken to investigate whether hepatocellular cholestasis induced in rats by ethynylestradiol ...