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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
(2016)
Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell ...
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
(2016)
Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell ...
Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies in chinese hamster ovary cells
(BioMed Central Ltd., 2019)
Background: The production of recombinant proteins in mammalian cell lines is one of the most important areas in biopharmaceutical industry. Viral transcriptional promoters are widely used to express recombinant proteins ...
Fluoride does not induce DNA breakage in Chinese hamster ovary cells in vitro.
(2004-07-01)
Fluoride has been widely used in dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury to genetic material. ...
Fluoride does not induce DNA breakage in Chinese hamster ovary cells in vitro.
(2004-07-01)
Fluoride has been widely used in dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury to genetic material. ...
Genotoxicity of corrosion eluates obtained from endosseous implants
(Lippincott Williams & Wilkins, 2007-03-01)
Purpose: Commercially pure titanium alloys are currently used as metallic biomaterials in implantology. Corrosion phenomena appear to play a decisive role in metallic implant long-term behavior. Thus, the goal of this study ...
Genotoxicity of corrosion eluates obtained from endosseous implants
(Lippincott Williams & Wilkins, 2007-03-01)
Purpose: Commercially pure titanium alloys are currently used as metallic biomaterials in implantology. Corrosion phenomena appear to play a decisive role in metallic implant long-term behavior. Thus, the goal of this study ...
Genotoxicity of Brosimum gaudichaudii measured by the Salmonella/microsome assay and chromosomal aberrations in CHO cells
(Elsevier B.V., 2002-07-01)
The root bark of Brosimum gaudichaudii Trecul (Moraceae) is popularly used for treatment of vitiligo. In the present study the mutagenic activity of the aqueous and methanolic extract as well as of the n-butanolic fraction ...