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Chemosensitizing activity of histone deacetylases inhibitory cyclic hydroxamic acids for combination chemotherapy of lymphatic leukemia
(Bentham Science Publishers B.V., 2018)
Decreased excitability of locus coeruleus neurons during hypercapnia is exaggerated in the streptozotocin-model of Alzheimer's disease
(2020-06-01)
The locus coeruleus (LC) is a pontine nucleus important for respiratory control and central chemoreception. It is affected in Alzheimer's disease (AD) and alteration of LC cell function may account for respiratory problems ...
Defining new criteria for selection of cell-based intestinal models using publicly available databases
(BioMed Central, 2012-06)
Background: The criteria for choosing relevant cell lines among a vast panel of available intestinal-derived lines exhibiting a wide range of functional properties are still ill-defined. The objective of this study was, ...
Evaluación del efecto del tratamiento combinado de mangiferina con cisplatino y 5-fluorouracilo en células CT26.WT y CHO-K1
(2014)
La mangiferina posee diferentes propiedades farmacológicas, y otras están por ser investigadas, tal como su actividad antitumoral como agente adyuvante a la quimioterapia antineoplásica convencional en la terapia combinada. ...
Anti-cancer mechanisms of linalool and 1,8-cineole in non-small cell lung cancer A549 cells
(Elsevier Science, 2020-12)
Linalool and 1,8-cineole are plant-derived isoprenoids with anticancer activities in lung cancer cells, nevertheless, the cellular and molecular mechanisms of action remain poorly understood. The purpose of this study was ...
Co2 decreases the activity of locus coeruleus neurons in the streptozotocin-induced model for Alzheimer's disease
(2019-01-01)
Introduction: Locus Coeruleus (LC) is an important chemosensitive nucleus and affected by neurodegenerative diseases like Alzheimer's disease (AD). LC dysfunction in AD may account for the respiratory problems observed in ...
Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells
(Oxford Univ PressOxfordInglaterra, 2006)
The alteration of neonatal raphe neurons by prenatal-perinatal nicotine. Meaning for sudden infant death syndrome
(American Thoracic Society, 2015)
Nicotine may link maternal cigarette smoking with respiratory dysfunctions in sudden infant death syndrome (SIDS). Prenatal-perinatal nicotine exposure blunts ventilatory responses to hypercapnia and reduces central ...